The ongoing COVID-19 pandemic, periodic recurrence of viral infections, and the
emergence of challenging variants has created an urgent need of alternative therapeutic …

Enteric symptomology seen in early-stage severe acute respiratory syndrome (SARS)-2003
and COVID-19 is evidence of virus replication occurring in the intestine, liver and pancreas …

Coronaviruses rely on host membranes for entry, establishment of replication centers, and
egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways …

It is urgent to develop disease models to dissect mechanisms regulating severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we derive airway …

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that has re-emerged in
recent decades, causing large-scale epidemics in many parts of the world. CHIKV infection …

Therapeutics targeting replication of SARS coronavirus 2 (SARS-CoV-2) are urgently
needed. Coronaviruses rely on host membranes for entry, establishment of replication …

Classical swine fever virus (CSFV), a member of the genus Pestivirus of the family
Flaviviridae, relies on host machinery to complete its life cycle. Previous studies have shown …

Lipids play essential roles in the cell as components of cellular membranes, signaling
molecules, and energy storage sources. Lipid droplets are cellular organelles composed of …

Chikungunya virus (CHIKV) infection causes chikungunya, a viral disease that currently has
no specific antiviral treatment. Several repurposed drug candidates have been investigated …

Mayaro virus is an emerging arbovirus that causes nonspecific febrile illness or arthralgia
syndromes similar to the Chikungunya virus, a virus closely related from the Togaviridae …