Diverse roles of UBE2T in cancer

N Ma, Z Li, J Yan, X Liu, L He, R Xie… - Oncology …, 2023 - spandidos-publications.com
As a leading cause of mortalities worldwide, cancer results from accumulation of both
genetic and epigenetic alterations. Disruption of epigenetic regulation in cancer, particularly …

[PDF][PDF] Unraveling the Role of Ubiquitin-Conjugating Enzyme UBE2T in Tumorigenesis: A Comprehensive Review

C Gao, YJ Liu, J Yu, R Wang, JJ Shi, RY Chen… - Cells, 2024 - researchgate.net
Ubiquitin-conjugating enzyme E2 T (UBE2T) is a crucial E2 enzyme in the ubiquitin-
proteasome system (UPS), playing a significant role in the ubiquitination of proteins and …

Ubiquitin-conjugating enzyme E2T confers chemoresistance of colorectal cancer by enhancing the signal propagation of Wnt/β-catenin pathway in an ERK-dependent …

B Liu, R Liu, X Zhang, L Tian, Z Li, J Yu - Chemico-Biological Interactions, 2024 - Elsevier
Chemotherapy is a major therapeutic option for colorectal cancer; however, the frequently
acquired chemoresistance greatly limits the treatment efficacy of chemotherapeutic agents …

TFAP2A downregulation mediates tumor-suppressive effect of miR-8072 in triple-negative breast cancer via inhibiting SNAI1 transcription

Y Fang, Y Wang, H Ma, Y Guo, R Xu, X Chen… - Breast Cancer …, 2024 - Springer
Background Triple-negative breast cancer (TNBC) represents a highly aggressive subset of
breast malignancies characterized by its challenging clinical management and unfavorable …

Leveraging diverse cellular stress patterns for predicting clinical outcomes and therapeutic responses in patients with multiple myeloma

J Xu, X Dong, J Dong, Y Peng, M Xing… - Journal of Cellular …, 2024 - Wiley Online Library
Tumour microenvironment harbours diverse stress factors that affect the progression of
multiple myeloma (MM), and the survival of MM cells heavily relies on crucial stress …

Gestational breast cancer: distinctive molecular and clinico-epidemiological features

JR de la Haba-Rodríguez, P Mínguez, F Rojo… - Journal of Mammary …, 2024 - Springer
Gestational breast cancer (GBC), defined as breast cancer (BC) diagnosed during
pregnancy or the first-year post-partum, accounts for 6–15% of BC cases in women aged 20 …

G1P3/IFI6, an interferon stimulated protein, promotes the association of RAB5+ endosomes with mitochondria in breast cancer cells

AM Davenport, M Morris, F Sabti, S Sabti… - Cell Biology …, 2023 - Wiley Online Library
Abstract G1P3/IFI6 is an interferon stimulated gene with antiapoptotic, prometastatic, and
antiviral functions. Despite its pleiotropic functions, subcellular localization of G1P3 remains …

基于转录组数据分析的妊娠乳腺癌复发关键基因识别研究.

尹金宝, 唐泽立, 梁兰 - Journal of Modern Medicine & …, 2024 - search.ebscohost.com
目的通过转录组数据分析, 识别妊娠乳腺癌复发的关键基因. 方法下载GEO
数据库中与妊娠乳腺癌相关的基因集GSE53031 的基因表达谱. 利用“limma” …

UBE2T mediates the stemness properties of breast cancer cells through the mTOR signaling pathway.

J YIN, Y WANG, G WEI, M WEN - Biocell, 2024 - search.ebscohost.com
Objectives: This study aimed to reveal the role and possible mechanism of the ubiquitin-
conjugating enzyme 2T (UBE2T) in the biological activities of breast cancer stem cells …