[HTML][HTML] Neoadjuvant radiotherapy for rectal cancer management

G Feeney, R Sehgal, M Sheehan, A Hogan… - World journal of …, 2019 - ncbi.nlm.nih.gov
Thirty per cent of all colorectal tumours develop in the rectum. The location of the rectum
within the bony pelvis and its proximity to vital structures presents significant therapeutic …

The incidence and risk factors of low anterior resection syndrome (LARS) after sphincter-preserving surgery of rectal cancer: a systematic review and meta-analysis

R Sun, Z Dai, Y Zhang, J Lu, Y Zhang, Y Xiao - Supportive Care in Cancer, 2021 - Springer
Background Many patients after sphincter-preserving surgery experienced anorectal
functional disturbances which were known as low anterior resection syndrome (LARS) …

[HTML][HTML] International consensus definition of low anterior resection syndrome

C Keane, NS Fearnhead, LG Bordeianou… - Diseases of the Colon …, 2020 - journals.lww.com
BACKGROUND: Low anterior resection syndrome is pragmatically defined as disordered
bowel function after rectal resection leading to a detriment in quality of life. This broad …

Role of circumferential margin involvement in the local recurrence of rectal cancer

IJ Adam, IG Martin, PJ Finan, D Johnston… - The Lancet, 1994 - Elsevier
Local recurrence after resection for rectal cancer remains common despite growing
acceptance that inadequate local excision may be implicated. In a prospective study of 190 …

Impact of a defunctioning ileostomy and time to stoma closure on bowel function after low anterior resection for rectal cancer: a systematic review and meta-analysis

I Vogel, N Reeves, PJ Tanis, WA Bemelman… - Techniques in …, 2021 - Springer
Background Impaired bowel function after low anterior resection (LAR) for rectal cancer is a
frequent problem with a major impact on quality of life. The aim of this study was to assess …

Low anterior resection syndrome

TH Nguyen, RV Chokshi - Current gastroenterology reports, 2020 - Springer
Abstract Purpose of Review Low anterior resection syndrome is a highly prevalent condition
that can develop after anal sphincter-sparing surgery for rectal cancer and impair quality of …

The impact of anastomotic leakage on long-term function after anterior resection for rectal cancer

DK Hultberg, J Svensson, H Jutesten… - Diseases of the Colon …, 2020 - journals.lww.com
BACKGROUND: It is still not clear whether anastomotic leakage after anterior resection for
rectal cancer affects long-term functional outcome. OBJECTIVE: This study aimed to …

Prevalence of low anterior resection syndrome and impact on quality of life after rectal cancer surgery: population-based study

EHA Pieniowski, C Nordenvall, G Palmer, A Johar… - BJS open, 2020 - academic.oup.com
Background The prevalence of major low anterior resection syndrome (LARS) after rectal
cancer surgery varies from 17· 8 to 56· 0 per cent, but data from high-quality studies are …

The role of pelvic floor muscle training on low anterior resection syndrome: a multicenter randomized controlled trial

A Asnong, A D'Hoore, M Van Kampen… - Annals of …, 2022 - journals.lww.com
Methods: A multicenter, single-blind prospective randomized controlled trial comparing
PFMT (intervention; n= 50) versus no PFMT (control; n= 54) 1 month following TME/stoma …

Functional complaints and quality of life after transanal total mesorectal excision: a meta-analysis

JAG Heijden, T Koëter, LJH Smits… - Journal of British …, 2020 - academic.oup.com
Background Total mesorectal excision (TME) gives excellent oncological results in rectal
cancer treatment, but patients may experience functional problems. A novel approach to …