[PDF][PDF] Physiologic activity of bisphosphonates–recent advances
E Chmielewska, P Kafarski - Open Pharmaceutical Sciences …, 2016 - benthamopen.com
Background: Bisphosphonates are drugs commonly used for the medication and prevention
of diseases caused by decreased mineral density. Despite such important medicinal use …
of diseases caused by decreased mineral density. Despite such important medicinal use …
5′-β, γ-CHF-ATP diastereomers: synthesis and fluorine-mediated selective binding by c-Src protein kinase
The first preparation of the individual β, γ-CHF-ATP stereoisomers 12a and 12b is reported.
Configurationally differing solely by the orientation of the C–F fluorine, 12a and 12b have …
Configurationally differing solely by the orientation of the C–F fluorine, 12a and 12b have …
Bromophosphoalkoxylation of olefins with organic phosphates, cyclic ethers and NBS
A variety of structurally novel phosphoalkoxy ester derivatives were prepared via highly
regio-and diastereoselective four-component reaction involving olefin, cyclic ether, halogen …
regio-and diastereoselective four-component reaction involving olefin, cyclic ether, halogen …
On the observation of discrete fluorine NMR Spectra for uridine 5′-β, γ-fluoromethylenetriphosphate diastereomers at basic pH
CS Hwang, BA Kashemirov… - The Journal of Organic …, 2014 - ACS Publications
Jakeman et al. recently reported the inability to distinguish the diastereomers of uridine 5′-
β, γ-fluoromethylenetriphosphate (β, γ-CHF-UTP, 1) by 19F NMR under conditions we …
β, γ-fluoromethylenetriphosphate (β, γ-CHF-UTP, 1) by 19F NMR under conditions we …
Four-component α-bromo-β-phosphoalkoxylation of aromatic α, β-unsaturated carbonyl compounds
Novel α-bromo-β-phosphoalkoxylated carbonyl compounds were produced in moderate to
excellent yields via highly selective four-component reaction involving NBS, a cyclic ether …
excellent yields via highly selective four-component reaction involving NBS, a cyclic ether …
Mechanistic variations of the bronsted linear free energy relationships for nonezymatic nucleotidyl transfer reactions
Z Zhang - 2016 - search.proquest.com
As the essential enzymes in human bodies, DNA polymerases play a significant role in DNA
replication, repair, genetic recombination, and reverse transcription. In 1956, the enzyme of …
replication, repair, genetic recombination, and reverse transcription. In 1956, the enzyme of …