Graph representation learning in bioinformatics: trends, methods and applications

HC Yi, ZH You, DS Huang… - Briefings in …, 2022 - academic.oup.com
Graph is a natural data structure for describing complex systems, which contains a set of
objects and relationships. Ubiquitous real-life biomedical problems can be modeled as …

Graph neural network approaches for drug-target interactions

Z Zhang, L Chen, F Zhong, D Wang, J Jiang… - Current Opinion in …, 2022 - Elsevier
Developing new drugs remains prohibitively expensive, time-consuming, and often involves
safety issues. Accurate prediction of drug-target interactions (DTIs) can guide the drug …

miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology

L Chang, G Zhou, O Soufan, J Xia - Nucleic acids research, 2020 - academic.oup.com
Abstract miRNet is an easy-to-use, web-based platform designed to help elucidate
microRNA (miRNA) functions by integrating users' data with existing knowledge via network …

A modern approach towards an industry 4.0 model: From driving technologies to management

G Tsaramirsis, A Kantaros, I Al-Darraji… - Journal of …, 2022 - Wiley Online Library
Every so often, a confluence of novel technologies emerges that radically transforms every
aspect of the industry, the global economy, and finally, the way we live. These sharp leaps of …

[HTML][HTML] A guide to conquer the biological network era using graph theory

M Koutrouli, E Karatzas, D Paez-Espino… - … in bioengineering and …, 2020 - frontiersin.org
Networks are one of the most common ways to represent biological systems as complex sets
of binary interactions or relations between different bioentities. In this article, we discuss the …

Circuit and molecular architecture of a ventral hippocampal network

MM Gergues, KJ Han, HS Choi, B Brown… - Nature …, 2020 - nature.com
The ventral hippocampus (vHPC) is a critical hub in networks that process emotional
information. While recent studies have indicated that ventral CA1 (vCA1) projection neurons …

[HTML][HTML] Microbiome multi-omics network analysis: statistical considerations, limitations, and opportunities

D Jiang, CR Armour, C Hu, M Mei, C Tian… - Frontiers in …, 2019 - frontiersin.org
The advent of large-scale microbiome studies affords newfound analytical opportunities to
understand how these communities of microbes operate and relate to their environment …

PaintOmics 4: new tools for the integrative analysis of multi-omics datasets supported by multiple pathway databases

T Liu, P Salguero, M Petek… - Nucleic Acids …, 2022 - academic.oup.com
PaintOmics is a web server for the integrative analysis and visualisation of multi-omics
datasets using biological pathway maps. PaintOmics 4 has several notable updates that …

Toward heterogeneous information fusion: bipartite graph convolutional networks for in silico drug repurposing

Z Wang, M Zhou, C Arnold - Bioinformatics, 2020 - academic.oup.com
Motivation Mining drug–disease association and related interactions are essential for
developing in silico drug repurposing (DR) methods and understanding underlying …

Methods for depicting overlap in overviews of systematic reviews: an introduction to static tabular and graphical displays

KI Bougioukas, E Vounzoulaki, CD Mantsiou… - Journal of Clinical …, 2021 - Elsevier
Abstract Background and Objective To introduce potential static tabular and graphical
techniques for visually presenting overlap between systematic reviews (SRs) included in …