Autism Spectrum Disorders (ASD) affect around 1.5% of the global population, which
manifest alterations in communication and socialization, as well as repetitive behaviors or …

Reelin is an extracellular matrix protein that is mainly produced in Cajal-Retzius cells and
controls neuronal migration, which is important for the proper formation of cortical layers in …

Schizophrenia (SCZ) is known to be a heritable disorder; however, its multifactorial nature
has significantly hampered attempts to establish its pathogenesis. Therefore, in this study …

Bipolar disorder (BP) and schizophrenia (SCZ) are major psychiatric disorders, but the
molecular mechanisms underlying the complicated pathologies of these disorders remain …

Abstract Background The chromosome 22q11. 2 deletion is an extremely high risk genetic
factor for various neuropsychiatric disorders; however, the 22q11. 2 deletion-related brain …

Reelin protein (RELN), an extracellular matrix protein, plays multiple roles that range from
embryonic neuronal migration to spine formation in the adult brain. Results from genetic …

Two of the primary features of Parkinson's disease (PD) are the accumulation of α-synuclein
(α-Syn) and the depletion of lysosomal-associated membrane protein 1 (LAMP1) in the …

Reelin is an extracellular matrix glycoprotein reduced in brain regions (the prefrontal cortex
and the hippocampus) of patients with schizophrenia. There are diverse rodent models of …

With recent advancements in psychiatric genomics, as a field,“stem cell-based disease
modelers” were given the exciting yet daunting task of translating the extensive list of …

Schizophrenia (SZ) is a prevalent functional psychosis characterized by clinical behavioural
symptoms and underlying abnormalities in brain function. Genome-wide association studies …