An overview and update on obesity and the obesity paradox in cardiovascular diseases

A Elagizi, S Kachur, CJ Lavie, S Carbone… - Progress in …, 2018 - Elsevier
Obesity increases a number of cardiovascular disease (CVD) risk factors, but patients with
many types of CVD may have a better prognosis if classified as overweight or obese, a …

Obesity paradox in cardiovascular disease: where do we stand?

S Carbone, JM Canada, HE Billingsley… - Vascular health and …, 2019 - Taylor & Francis
Obesity is associated with an increased risk of developing cardiovascular disease (CVD),
particularly heart failure (HF) and coronary heart disease (CHD). The mechanisms through …

Exercise and the cardiovascular system: clinical science and cardiovascular outcomes

CJ Lavie, R Arena, DL Swift, NM Johannsen… - Circulation …, 2015 - Am Heart Assoc
Substantial evidence has established the value of high levels of physical activity, exercise
training (ET), and overall cardiorespiratory fitness in the prevention and treatment of …

Physical activity and cardiorespiratory fitness as major markers of cardiovascular risk: their independent and interwoven importance to health status

J Myers, P McAuley, CJ Lavie, JP Despres… - Progress in …, 2015 - Elsevier
The evolution from hunting and gathering to agriculture, followed by industrialization, has
had a profound effect on human physical activity (PA) patterns. Current PA patterns are …

Obesity and prevalence of cardiovascular diseases and prognosis—the obesity paradox updated

CJ Lavie, A De Schutter, P Parto, E Jahangir… - Progress in …, 2016 - Elsevier
The prevalence and severity of obesity have increased in the United States and most of the
Westernized World over recent decades, reaching worldwide epidemics. Since obesity …

Etiology of metabolic syndrome and dietary intervention

H Xu, X Li, H Adams, K Kubena, S Guo - International journal of molecular …, 2018 - mdpi.com
The growing prevalence of metabolic syndrome (MetS) in the US and even worldwide is
becoming a serious health problem and economic burden. MetS has become a crucial risk …

Obesity and cardiovascular diseases: implications regarding fitness, fatness, and severity in the obesity paradox

CJ Lavie, PA McAuley, TS Church, RV Milani… - Journal of the American …, 2014 - jacc.org
Obesity has been increasing in epidemic proportions, with a disproportionately higher
increase in morbid or class III obesity, and obesity adversely affects cardiovascular (CV) …

Obesity or BMI paradox? Beneath the tip of the iceberg

LM Donini, A Pinto, AM Giusti, A Lenzi… - Frontiers in …, 2020 - frontiersin.org
The obesity paradox refers to extant evidence showing that obesity in older subjects or in
patients with several chronic diseases may be protective and associated with decreased …

Body mass index, the most widely used but also widely criticized index: would a criterion standard measure of total body fat be a better predictor of cardiovascular …

FB Ortega, X Sui, CJ Lavie, SN Blair - Mayo Clinic Proceedings, 2016 - Elsevier
Objectives To examine whether an accurate measure (using a criterion standard method) of
total body fat would be a better predictor of cardiovascular disease (CVD) mortality than …

Association of body mass index with cardiometabolic disease in the UK Biobank: a Mendelian randomization study

DM Lyall, C Celis-Morales, J Ward, S Iliodromiti… - JAMA …, 2017 - jamanetwork.com
Importance Higher body mass index (BMI) is a risk factor for cardiometabolic disease;
however, the underlying causal associations remain unclear. Objectives To use UK Biobank …