The expanding CRISPR toolbox for natural product discovery and engineering in filamentous fungi

C Woodcraft, YH Chooi, I Roux - Natural Product Reports, 2023 - pubs.rsc.org
Covering: up to May 2022 Fungal genetics has transformed natural product research by
enabling the elucidation of cryptic metabolites and biosynthetic steps. The enhanced …

Epipolythiodioxopiperazine‐Based Natural Products: Building Blocks, Biosynthesis and Biological Activities

EM Huber - ChemBioChem, 2022 - Wiley Online Library
Epipolythiodioxopiperazines (ETPs) are fungal secondary metabolites that share a 2, 5‐
diketopiperazine scaffold built from two amino acids and bridged by a sulfide moiety …

Gliotoxin, an Immunosuppressive Fungal Metabolite, Primes Plant Immunity: Evidence from Trichoderma virens-Tomato Interaction

R Zaid, R Koren, E Kligun, R Gupta… - MBio, 2022 - Am Soc Microbiol
Beneficial interaction of members of the fungal genus Trichoderma with plant roots primes
the plant immune system, promoting systemic resistance to pathogen infection. Some strains …

Co‐inoculation timing affects the interspecific interactions between phoma stem canker pathogens Leptosphaeria maculans and Leptosphaeria biglobosa

E Bingol, A Qi, C Karandeni‐Dewage… - Pest management …, 2024 - Wiley Online Library
BACKGROUND Phoma stem canker is an economically important disease of oilseed rape,
caused by two co‐existing fungal pathogen species, Leptosphaeria maculans (Plenodomus …

Unveiling the Virulence Mechanism of Leptosphaeria maculans in the Brassica napus Interaction: The Key Role of Sirodesmin PL in Cell Death Induction

MA Pombo, HG Rosli, S Maiale, C Elliott… - Journal of …, 2024 - academic.oup.com
Leptosphaeria maculans is the causal agent of blackleg disease in Brassica napus, leading
to substantial yield losses. Sirodesmin PL, the principal toxin produced by L. maculans, has …

The novel avirulence effector AlAvr1 from Ascochyta lentis mediates host cultivar specificity of ascochyta blight in lentil

BM Henares, JW Debler… - Molecular Plant …, 2022 - Wiley Online Library
Ascochyta lentis is a fungal pathogen that causes ascochyta blight in the important grain
legume species lentil, but little is known about the molecular mechanism of disease or host …

Formation of Bridged Disulfide in Epidithiodioxopiperazines

J Fan, PL Wei, WB Yin - ChemBioChem, 2024 - Wiley Online Library
Epidithiodioxopiperazine (ETP) alkaloids, featuring a 2, 5‐diketopiperazine core and
transannular disulfide bridge, exhibit a broad spectrum of biological activities. However, the …

[PDF][PDF] Co-inoculation timing affects the interspecific interactions between phoma stem canker

E Bingol, A Qi, C Karandeni-Dewage, F Ritchie… - 2023 - researchgate.net
BACKGROUND: Phoma stem canker is an economically important disease of oilseed rape,
caused by two co-existing fungal pathogen species, Leptosphaeria maculans (Plenodomus …