Structural insights into actin filament turnover

W Oosterheert, MB Sanders, P Bieling, S Raunser - Trends in Cell Biology, 2025 - cell.com
The dynamic turnover of actin filaments drives the morphogenesis and migration of all
eukaryotic cells. This review summarizes recent insights into the molecular mechanisms of …

Megamolecule Self-Assembly Networks: A Combined Computational and Experimental Design Strategy

J Wu, Z Gu, JA Modica, S Chen… - Journal of the …, 2024 - ACS Publications
This work describes the use of computational strategies to design megamolecule building
blocks for the self-assembly of lattice networks. The megamolecules are prepared by …

Molecular simulation approaches to probing the effects of mechanical forces in the actin cytoskeleton

F Mukadum, WJP Ccoa… - Cytoskeleton (Hoboken …, 2024 - pmc.ncbi.nlm.nih.gov
Molecular simulation approaches to probing the effects of mechanical forces in the actin
cytoskeleton - PMC Skip to main content Here's how you know Official websites use .gov A .gov …

Data-Driven Equation-Free Dynamics Applied to Many-Protein Complexes: The Microtubule Tip Relaxation

J Wu, S Dasetty, D Beckett, Y Wang, W Xue, T Skóra… - Biophysical …, 2025 - cell.com
Microtubules (MTs) constitute the largest components of the eukaryotic cytoskeleton and
play crucial roles in various cellular processes, including mitosis and intracellular transport …

Cryo-EM reconstruction of yeast ADP-actin filament at 2.5 Å resolution. A comparison with vertebrate F-actin

SR Stevenson, SB Tzokov, I Lahiri, KR Ayscough… - Structure, 2025 - cell.com
The core component of the actin cytoskeleton is the globular protein G-actin, which
reversibly polymerizes into filaments (F-actin). Budding yeast possesses a single actin that …