Transthyretin amyloid cardiomyopathy (ATTR-CM) results in a restrictive cardiomyopathy
caused by extracellular deposition of transthyretin, normally involved in the transportation of …

Aims An algorithm for non‐invasive diagnosis of amyloid transthyretin cardiac amyloidosis
(ATTR‐CA) and novel disease‐modifying therapies have prompted an active search for CA …

The systemic amyloidoses are a broad spectrum of diseases that result from misfolding of
proteins that aggregate into b-sheet amyloid fibrils. Over 35 amyloidogenic precursor …

Nearly half of all patients with heart failure (HF) have a normal left ventricular (LV) ejection
fraction (EF) and the condition is termed heart failure with preserved ejection fraction …

Transthyretin cardiac amyloidosis (ATTR-CA) is increasingly diagnosed owing to the
emergence of noninvasive imaging and improved awareness. Clinical penetrance of …

Transthyretin cardiac amyloidosis (ATTR-CA) is an increasingly recognized cause of heart
failure (HF) and mortality worldwide. Advances in non-invasive diagnosis, coupled with the …

Aim The diagnosis, severity and extent of a sterile inflammation or a septic infection could be
challenging since there is not one single test able to achieve an accurate diagnosis. The …

[CQ1] What is the role of 99 mTc-PYP scintigraphy (bone scintigraphy) in clinical practice for
CA?∙∙∙∙∙∙ 1655 [CQ2] The role of endomyocardial biopsy. Which site is appropriate for biopsy …

Technetium-labeled cardiac scintigraphy (ie, Tc-PYP scan) has been repurposed for the
diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM). Validated in cohorts of …

Aims Cardiac amyloidosis is common in elderly patients with aortic stenosis (AS) referred for
transcatheter aortic valve implantation (TAVI). We hypothesized that patients with dual aortic …