Sand flies: Basic information on the vectors of leishmaniasis and their interactions with Leishmania parasites

P Cecílio, A Cordeiro-da-Silva, F Oliveira - Communications biology, 2022 - nature.com
Blood-sucking arthropods transmit a variety of human pathogens acting as disseminators of
the so-called vector-borne diseases. Leishmaniasis is a spectrum of diseases caused by …

Engineered macromolecular Toll-like receptor agents and assemblies

BAJ Hoffman, EA Pumford, AI Enueme, KL Fetah… - Trends in …, 2023 - cell.com
Macromolecular Toll-like receptor (TLR) agents have been utilized as agonists and
inhibitors in preclinical and clinical settings. These agents interface with the TLR class of …

Immunotherapy for visceral leishmaniasis: A trapeze of balancing counteractive forces

PH Mazire, B Saha, A Roy - International immunopharmacology, 2022 - Elsevier
The protozoan parasite Leishmania donovani, residing and replicating within the cells of the
monocyte-macrophage (mono-mac) lineage, causes visceral leishmaniasis (VL) in humans …

[HTML][HTML] An overview of the sand fly salivary proteins in vaccine development against leishmaniases

S Fayaz, F Bahrami, P Parvizi… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
Leishmaniases are a group of vector-borne parasitic diseases transmitted through the
infected sand flies. Leishmania parasites are inoculated into the host skin along with sand fly …

Unleashing the role of potential adjuvants in leishmaniasis

I Saini, J Joshi, S Kaur - International Journal of Pharmaceutics, 2024 - Elsevier
Leishmaniasis is amongst one of the most neglected tropical disease, caused by an
intracellular protozoan of genus Leishmania. Currently, the most promising strategy to …

Ayaconin, a novel inhibitor of the plasma contact system from the sand fly Lutzomyia ayacuchensis, a vector of Andean-type cutaneous leishmaniasis

S Kawahori, C Seki, D Mizushima, A Tabbabi… - Acta Tropica, 2022 - Elsevier
Transcriptome analysis of the salivary gland cDNA library from a phlebotomine sand fly,
Lutzomyia ayacuchensis, identified a transcript coding for the PpSP15/SL1 family protein as …

Some good and some bad: Sand fly salivary proteins in the control of leishmaniasis and in autoimmunity

V Aoki, M Abdeladhim, N Li, P Cecilio… - Frontiers in cellular …, 2022 - frontiersin.org
Sand flies are hematophagous insects responsible for the transmission of vector-borne
diseases to humans. Prominent among these diseases is Leishmaniasis that affects the skin …

Leishmania infantum infection does not affect the main composition of the intestinal microbiome of the Syrian hamster

AI Olías-Molero, P Botías, M Cuquerella… - Parasites & …, 2022 - Springer
Background Visceral leishmaniasis (VL) is the most severe form of all leishmanial infections
and is caused by infection with protozoa of Leishmania donovani and Leishmania infantum …

Leishmania–sand fly interactions: exploring the role of the immune response and potential strategies for Leishmaniasis control

R Sabbahi, V Hock, K Azzaoui, B Hammouti - Journal of Parasitic …, 2024 - Springer
Leishmaniasis is a neglected tropical disease caused by protozoan parasites of the genus
Leishmania, affecting millions of people worldwide. The disease is transmitted by the bite of …

Advances in Leishmania Research: From Basic Parasite Biology to Disease Control

N Santarém, L Cardoso, A Cordeiro-da-Silva - Microorganisms, 2023 - mdpi.com
The genus Leishmania (Trypanosomatida: Trypanosomatidae) currently comprises just over
50 species, of which about 20 cause several syndromes in humans, collectively known as …