The imidazo [1, 2-a] pyridine scaffold is recognized as a privileged structure as it represents
a promising area for identification of lead structures towards the discovery of new synthetic …

This review surveys recent developments (reported in the last fifteen years) in
organometallic‐chemistry‐based methods for the functionalization of imidazo [1, 2‐a] …

A series of new blue-phosphorescent iridium (III) complexes 1− 14 with ligands of 2-
phenylimidazo [1, 2-a] pyridine (pip) derivatives were successfully prepared, and their …

Mild, efficient, copper‐catalyzed N‐arylation procedures for nitrogen heterocycles, amides,
carbamates, and C‐arylation procedures for malonic acid derivatives have been developed …

We describe herein the design, synthesis and pharmacological evaluation of novel 3-
arylamine-imidazo [1, 2-a] pyridine derivatives structurally designed as novel symbiotic …

8-Fluoroimidazo [1, 2-a] pyridine has been established as a physicochemical mimic of
imidazo [1, 2-a] pyrimidine, using both in silico and traditional techniques. Furthermore, a …

The therapy of chronic inflammatory diseases like rheumatoid arthritis (RA) and
inflammatory bowel disease (IBD) has recently been enriched by the successful launch of …

The recent successful introduction of the anti‐cytokine biologicals Etanercept, Infliximab,
Adalimumab, and Anakinra has stimulated the search for anti‐cytokine small‐molecules. A …

Direct C-3 arylation of imidazo [1, 2-a] pyridines with aryl tosylates and mesylates has been
accomplished by employing palladium (II) acetate associated with SPhos (2 …

Abstract A series of 16 novel 1, 2, 4-triazine derivatives bearing hydrazone moiety (7a–7p)
have been designed, synthesized and evaluated for their activity to inhibit IL-1β and TNF-α …