Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

The lifelong health of an individual is shaped during critical periods of development. The
fetus is particularly susceptible to internal and external stimuli, many of which can alter …

Recent and accumulating work in experimental animal models and humans shows that diet
has a much more pervasive and prominent role than previously thought in modulating …

Dietary interventions have emerged as effective environmental inducers of brain plasticity.
Among these dietary interventions, we here highlight the impact of caloric restriction (CR: a …

During development of the nervous system, the formation of connections (synapses)
between neurons is dependent upon electrical activity in those neurons, and neurotrophic …

Dietary restriction (DR) has long been viewed as the most robust nongenetic means to
extend lifespan and healthspan. Many aging-associated mechanisms are nutrient …

Nuclear factor erythroid 2-related factor 2 (Nrf2) regulates the expression of an array of
enzymes with important detoxifying and antioxidant functions. Current findings support the …

Background: Due to the increased life expectancy, the prevalence of aging-related health
conditions, such as cognitive impairment, dementia and Alzheimer's disease is increasing …

Numerous studies of animal models have demonstrated the importance of glutamate
receptor activation/excitotoxicity in the death of neurons in severe epileptic seizures, as well …

Major depression is thought to originate from maladaptation to adverse events, particularly
when impairments occur in mood-related brain regions. Hypothalamus–pituitary–adrenal …