Recent advances in the use of dimethyl sulfoxide as a synthon in organic chemistry

H Lu, Z Tong, L Peng, Z Wang, SF Yin… - Topics in Current …, 2022 - Springer
Dimethyl sulfoxide (DMSO), as extremely important aprotic polar solvent and reaction
medium, has attracted widespread attention from chemists in recent years due to its wide …

Manufacturing Process Development for the Biaryl Ether Fragment of Nemtabrutinib (MK-1026)

NR Deprez, HB Rose, BK Peters… - … Process Research & …, 2023 - ACS Publications
MK-1026, also known as nemtabrutinib (1), has been developed as a reversible Bruton's
tyrosine kinase (BTK) inhibitor for the treatment of chronic lymphocytic leukemia. This article …

Reverse Temperature Solution to Grow High-Quality CsCu2I3 Single Crystal with Formic Acid for Radiation Detection

J Lai, L Yang, W Wang, S Wang, Y Lu… - Crystal Growth & …, 2024 - ACS Publications
One-dimensional (1D) CsCu2I3 single crystals (SCs) have been investigated as novel
sensitive X-ray and γ-ray scintillators, which can be prepared by the Bridgman method and …

Manufacturing Process for 6-Bromo-N,N-bis(4-methoxybenzyl)-4-methyl-5-(trifluoromethyl)pyridin-2-amine, a Key Intermediate in the Synthesis of KRAS G12C …

J Shen, NA White, Q Tian, LE Sirois… - … Process Research & …, 2023 - ACS Publications
The densely functionalized heterocycle 6-bromo-N, N-bis (4-methoxybenzyl)-4-methyl-5-
(trifluoromethyl) pyridin-2-amine (1) represents a key intermediate in the atroposelective …

Intramolecular Dehydrogenative Photocyclization of N-Phenyl-1-naphthamides

HY Li, X Niu, SS Zhang, S Shen, QY Meng… - Organic …, 2024 - ACS Publications
Here, we explore a dehydrogenative 6π photocyclization method for N-substituted
naphthalene carboxamides, which can be conducted in air. This method employs DMSO as …

Low-Temperature Plasma Modification of Lignin-Derived Carbon Solid Acid Catalyst for Catalytic Production of 5-HMF

S Lv, X Deng, P Zhu, L Ruan, Y Tao, L Wang, J Zhu… - Catalysis Letters, 2024 - Springer
Sulfonated carbon catalysts exhibit superior catalytic performance for production of
biobased chemicals, but the catalyst preparation approaches are still suffered from high …

Oxidation of dimethylsulfoxide in the presence of uranyl salts

A Raghavan, CL Cahill - Polyhedron, 2023 - Elsevier
We report here the oxidation of dimethyl sulfoxide in the presence of uranyl salts at
temperatures typically considered 'safe'for its handling. Uranyl salts, even in the absence of …

Redox‐Neutral Carboxylation of Benzylic Tertiary C‐H Bonds with Carbon Dioxide

QY Meng, JL Li, SS Zhang, LL Jiang, HY Li… - Angewandte … - Wiley Online Library
The direct catalytic carboxylation of benzylic tertiary C‐H bonds with CO2 for the synthesis of
all‐carbon quaternary carboxylic acids represents a significant challenge. Here, we present …