Precise gene expression ensures proper stem and progenitor cell differentiation, lineage
commitment and organogenesis during mammalian development. ATP-dependent …

Follicular growth and oogenesis involve highly dynamic changes in morphogenesis,
chromatin structure, and gene transcription. The tight coordination of these events leads to …

Epigenetic reprogramming plays a pivotal role during embryogenesis, including both
covalent and non-covalent modifications to chromatin. In this study, we investigated the role …

The estrous cycle is regulated by rhythmic endocrine interactions of the nervous and
reproductive systems, which coordinate the hormonal and ovulatory functions of the ovary …

Ovarian cancer (OC) is the fifth leading cause of women's death from cancers. The high
mortality rate is attributed to the late presence of the disease and the lack of modern …

The specific location of nucleosomes on DNA has important inhibitory or activating roles in
the regulation of DNA‐dependent processes as it affects the DNA accessibility. Nucleosome …

An essential component of the chromatin remodeling machinery is NURF (Nucleosome
Remodeling Factor), the founding member of the ISWI family of chromatin remodeling …

Abstract The mammalian ISWI (Imitation Switch) genes SMARCA1 and SMARCA5 encode
the ATP-dependent chromatin remodeling proteins SNF2L and SNF2H. The ISWI proteins …

Background Progesterone, via its nuclear receptor (PR), exerts an overall tumorigenic effect
on both uterine fibroid (leiomyoma) and breast cancer tissues, whereas the antiprogestin …

Chromatin-remodelling mechanisms include DNA methylation, histone-tail acetylation, poly-
ADP-ribosylation, and ATP-dependent chromatin-remodelling processes. Some epigenetic …