Preconditioning, postconditioning, and remote conditioning of the myocardium enhance the
ability of the heart to withstand a prolonged ischemia/reperfusion insult and the potential to …

Alzheimer's disease (AD) is one of the most common neurodegenerative pathologies. Its
incidence is in dramatic growth in Western societies and there is a need of both biomarkers …

Gout flares require monosodium urate (MSU) to activate the NLRP3 inflammasome and
secrete sufficient IL-1β. However, MSU alone is not sufficient to cause a flare. This is …

Increasing evidence demonstrated the relevance of adenosine system in the onset and
development of cardiovascular diseases, such as hypertension, myocardial infarct …

Atrial fibrillation (AF) is a cardiac arrhythmia caused by electrophysiological anomalies in the
atrial tissue, tissue degradation, structural abnormalities, and comorbidities. A direct …

Atrial fibrillation (AF) is the most common arrhythmia in the world. Because the key to
developing innovative therapies that limit the onset and the progression of AF is to fully …

Adenosine, an endogenous nucleoside, plays a critical role in maintaining homeostasis
during stressful situations, such as energy deprivation or cellular damage. Therefore …

While the concept of a receptor reserve (spare receptors) is old, their presence on human
cells as an adaptive mechanism in cardiovascular disease is a new suggestion. The …

Increased adenosine A2A receptor (A2AR) expression and activation underlies a higher
incidence of spontaneous calcium release in atrial fibrillation (AF). Adenosine A3 receptors …

Background Several published studies have examined the association of coffee
consumption with atrial fibrillation (AF) risk, but their findings are still controversial …