Structural and functional aspects of Ebola virus proteins

S Jain, E Martynova, A Rizvanov, S Khaiboullina… - Pathogens, 2021 - mdpi.com
Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented,
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …

Structures of the Mononegavirales Polymerases

B Liang - Journal of Virology, 2020 - Am Soc Microbiol
Mononegavirales, known as nonsegmented negative-sense (NNS) RNA viruses, are a class
of pathogenic and sometimes deadly viruses that include rabies virus (RABV), human …

Ebola viral glycoprotein bound to its endosomal receptor Niemann-Pick C1

H Wang, Y Shi, J Song, J Qi, G Lu, J Yan, GF Gao - Cell, 2016 - cell.com
Summary Filoviruses, including Ebola and Marburg, cause fatal hemorrhagic fever in
humans and primates. Understanding how these viruses enter host cells could help to …

Structure of the Ebola virus polymerase complex

B Yuan, Q Peng, J Cheng, M Wang, J Zhong, J Qi… - Nature, 2022 - nature.com
Filoviruses, including Ebola virus, pose an increasing threat to the public health. Although
two therapeutic monoclonal antibodies have been approved to treat the Ebola virus …

[HTML][HTML] Longitudinal analysis of the human B cell response to Ebola virus infection

CW Davis, KJL Jackson, AK McElroy, P Halfmann… - Cell, 2019 - cell.com
Ebola virus (EBOV) remains a public health threat. We performed a longitudinal study of B
cell responses to EBOV in four survivors of the 2014 West African outbreak. Infection …

Structure and assembly of the Ebola virus nucleocapsid

W Wan, L Kolesnikova, M Clarke, A Koehler, T Noda… - Nature, 2017 - nature.com
Ebola and Marburg viruses are filoviruses: filamentous, enveloped viruses that cause
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …

Cryo-EM structure of the Ebola virus nucleoprotein–RNA complex at 3.6 Å resolution

Y Sugita, H Matsunami, Y Kawaoka, T Noda, M Wolf - Nature, 2018 - nature.com
Ebola virus causes haemorrhagic fever with a high fatality rate in humans and non-human
primates. It belongs to the family Filoviridae in the order Mononegavirales, which are viruses …

Intracellular Ebola Virus nucleocapsid assembly revealed by in situ cryo-electron tomography

R Watanabe, D Zyla, D Parekh, C Hong, Y Jones… - Cell, 2024 - cell.com
Filoviruses, including the Ebola and Marburg viruses, cause hemorrhagic fevers with up to
90% lethality. The viral nucleocapsid is assembled by polymerization of the nucleoprotein …

The C-terminal LCAR of host ANP32 proteins interacts with the influenza A virus nucleoprotein to promote the replication of the viral RNA genome

F Wang, CM Sheppard, B Mistry, E Staller… - Nucleic acids …, 2022 - academic.oup.com
The segmented negative-sense RNA genome of influenza A virus is assembled into
ribonucleoprotein complexes (RNP) with viral RNA-dependent RNA polymerase and …

The host E3-ubiquitin ligase TRIM6 ubiquitinates the Ebola virus VP35 protein and promotes virus replication

P Bharaj, C Atkins, P Luthra, MI Giraldo… - Journal of …, 2017 - Am Soc Microbiol
Ebola virus (EBOV), a member of the Filoviridae family, is a highly pathogenic virus that
causes severe hemorrhagic fever in humans and is responsible for epidemics throughout …