Leprosy, a disease caused by the intracellular parasite Mycobacterium leprae or
Mycobacterium lepromatosis, has affected humans for more than 4,000 years and is a …

Leprosy is a chronic infectious disease of the skin and peripheral nerves that presents a
strong link with the host genetic background. Different approaches in genetic studies have …

Emerging diseases have significantly impacted the last few decades (1–10). The emergence
and re-emergence of vector-borne and zoonotic diseases in Africa, Asia, and Latin America …

The pathways that trigger exacerbated immune reactions in leprosy could be determined by
genetic variations. Here, in a prospective approach, both genetic and non-genetic variables …

Genetics plays a crucial role in controlling susceptibility to infectious diseases by modulating
the interplay between humans and pathogens. This is particularly evident in leprosy, since …

In Mycobacterium tuberculosis (MTB) infection, the complex interaction of host immune
system and the mycobacteria is associated with levels of cytokines production that play a …

Host genetic susceptibility to leprosy has been intensively investigated over the last
decades; however, there are no studies on the role of genetic variants in disease …

Leprosy is a chronic infectious disease, caused by Mycobacterium leprae, which affects skin
and peripheral nerves. Polymorphisms in genes associated with autophagy, metabolism …

Objective Acute necrotizing encephalopathy (ANE) is a severe complication of infectious
diseases affecting the brain and systemic organs. The main pathogenesis is cytokine storm …

Leprosy continues to be an important health issue in several endemic countries. The global
incidence of this disease is greater than 200,000 new cases detected annually. This number …