Non-coding RNAs generally form ribonucleoprotein (RNP) complexes with their partner
proteins to exert their functions. Small RNAs, including microRNAs, small interfering RNAs …

RNA silencing is a eukaryote‐specific phenomenon in which microRNAs and small
interfering RNAs degrade messenger RNAs containing a complementary sequence. To this …

Understanding the function of the thousands of cellular proteins is a central question in
molecular cell biology. As proteins are typically part of multiple dynamic and often …

Programmed genome rearrangements in ciliates provide fascinating examples of flexible
epigenetic genome regulations and important insights into the interaction between …

Abstract Argonaute 1 (AGO1), the principal protein component of microRNA-mediated
regulation, plays a key role in plant growth and development. AGO1 physically interacts with …

Epigenetic research focuses on heritable changes beyond the DNA sequence, which has
led to a revolution in biological studies and benefits in many other fields. The well-known …

Small RNAs are used to silence transposable elements (TEs) in many eukaryotes, which
use diverse evolutionary solutions to identify TEs. In ciliated protozoans, small-RNA …

Lysine methylation of histones and non-histones plays a pivotal role in diverse cellular
processes. The SMYD (SET and MYND domain) family methyltransferases can methylate …

Heterochromatic loci are often assembled into higher-order heterochromatin bodies in
diverse eukaryotes. However, the formation and biological roles of heterochromatin bodies …

Tetrahymena is a useful eukaryotic model for biochemistry and molecular cell biology
studies. We previously demonstrated that targeted ectopic DNA elimination, also called co …