MR Miller, IL Megson - British journal of pharmacology, 2007 - Wiley Online Library
During the 1980s, the free radical, nitric oxide (NO), was discovered to be a crucial signalling molecule, with wide‐ranging functions in the cardiovascular, nervous and immune …
A Tursi, G Brandimarte, A Papa, A Giglio… - Official journal of the …, 2010 - journals.lww.com
OBJECTIVES: VSL# 3 is a high-potency probiotic mixture that has been used successfully in the treatment of pouchitis. The primary end point of the study was to assess the effects of …
A Sood, V Midha, GK Makharia, V Ahuja… - Clinical …, 2009 - Elsevier
BACKGROUND & AIMS: Probiotics effectively can maintain remission in patients with ulcerative colitis (UC), but little is known of their ability to induce remission. We conducted a …
JL Wallace, MJS Miller - Gastroenterology, 2000 - Elsevier
Nitric oxide (NO) is now recognized as an important modulator of an enormous number of physiological processes, ranging from blood pressure regulation to neuronal transmission to …
Nitric oxide (NO), a signaling molecule, regulates biological functions in multiple organs/tissues, including the epidermis, where it impacts permeability barrier homeostasis …
J Fioramonti, V Theodorou, L Bueno - Best Practice & Research Clinical …, 2003 - Elsevier
Probiotics can be defined as microbial cells that have a beneficial effect on the health and well-being of the host. Since the gastrointestinal mucosa is the surface of contact with …
C De Santo, P Serafini, I Marigo… - Proceedings of the …, 2005 - National Acad Sciences
Active suppression of tumor-specific T lymphocytes can limit the immune-mediated destruction of cancer cells. Of the various strategies used by tumors to counteract immune …
S Fiorucci, S Orlandi, A Mencarelli… - British journal of …, 2007 - Wiley Online Library
Background and Purpose: Mesalamine is the first‐line therapy for colitis, but it lacks potency and is only effective for mild‐to‐moderate forms of this disease. Hydrogen sulphide has …
GR Martin, JL Wallace - Experimental Biology and Medicine, 2006 - journals.sagepub.com
The mucosal layer of the gastrointestinal (GI) tract is able to resist digestion by the endogenous substances that we secrete to digest foodstuffs. So-called “mucosal defense” is …