Nitric oxide donors: chemical activities and biological applications

PG Wang, M Xian, X Tang, X Wu, Z Wen, T Cai… - Chemical …, 2002 - ACS Publications
Nitric Oxide Donors: Chemical Activities and Biological Applications | Chemical Reviews ACS
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Recent developments in nitric oxide donor drugs

MR Miller, IL Megson - British journal of pharmacology, 2007 - Wiley Online Library
During the 1980s, the free radical, nitric oxide (NO), was discovered to be a crucial
signalling molecule, with wide‐ranging functions in the cardiovascular, nervous and immune …

Treatment of relapsing mild-to-moderate ulcerative colitis with the probiotic VSL# 3 as adjunctive to a standard pharmaceutical treatment: a double-blind, randomized …

A Tursi, G Brandimarte, A Papa, A Giglio… - Official journal of the …, 2010 - journals.lww.com
OBJECTIVES: VSL# 3 is a high-potency probiotic mixture that has been used successfully in
the treatment of pouchitis. The primary end point of the study was to assess the effects of …

The probiotic preparation, VSL# 3 induces remission in patients with mild-to-moderately active ulcerative colitis

A Sood, V Midha, GK Makharia, V Ahuja… - Clinical …, 2009 - Elsevier
BACKGROUND & AIMS: Probiotics effectively can maintain remission in patients with
ulcerative colitis (UC), but little is known of their ability to induce remission. We conducted a …

Nitric oxide in mucosal defense: a little goes a long way

JL Wallace, MJS Miller - Gastroenterology, 2000 - Elsevier
Nitric oxide (NO) is now recognized as an important modulator of an enormous number of
physiological processes, ranging from blood pressure regulation to neuronal transmission to …

Regulatory role of nitric oxide in cutaneous inflammation

MQ Man, JS Wakefield, TM Mauro, PM Elias - Inflammation, 2022 - Springer
Nitric oxide (NO), a signaling molecule, regulates biological functions in multiple
organs/tissues, including the epidermis, where it impacts permeability barrier homeostasis …

Probiotics: what are they? What are their effects on gut physiology?

J Fioramonti, V Theodorou, L Bueno - Best Practice & Research Clinical …, 2003 - Elsevier
Probiotics can be defined as microbial cells that have a beneficial effect on the health and
well-being of the host. Since the gastrointestinal mucosa is the surface of contact with …

Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination

C De Santo, P Serafini, I Marigo… - Proceedings of the …, 2005 - National Acad Sciences
Active suppression of tumor-specific T lymphocytes can limit the immune-mediated
destruction of cancer cells. Of the various strategies used by tumors to counteract immune …

Enhanced activity of a hydrogen sulphide‐releasing derivative of mesalamine (ATB‐429) in a mouse model of colitis

S Fiorucci, S Orlandi, A Mencarelli… - British journal of …, 2007 - Wiley Online Library
Background and Purpose: Mesalamine is the first‐line therapy for colitis, but it lacks potency
and is only effective for mild‐to‐moderate forms of this disease. Hydrogen sulphide has …

Gastrointestinal inflammation: a central component of mucosal defense and repair

GR Martin, JL Wallace - Experimental Biology and Medicine, 2006 - journals.sagepub.com
The mucosal layer of the gastrointestinal (GI) tract is able to resist digestion by the
endogenous substances that we secrete to digest foodstuffs. So-called “mucosal defense” is …