Cardiovascular diseases burden is increasing due to aging populations and represents one
of the major health issues worldwide. Dietary habits have been extensively studied in the …

Background/Objectives. This paper seeks to identify the prevalence of Phenylketonuria
(PKU) in Arab countries, Turkey, and Iran. The study reviewed the existence of …

To date more than 1000 different variants in the PAH gene have been identified in patients
with phenylketonuria (PKU). In Iran, several studies have been performed to investigate the …

Identification of molecular basis of phenylketonuria (PKU) in Iran has been accomplished
through the analysis of 248 unrelated chromosomes from 124 Iranian classic PKU subjects …

Background: Phenylketonuria is a hereditary, autosomal recessive disorder caused by
deficiency of phenylalanine hydroxylase or its cofactor tetrahydrobiopterin. The purpose of …

The cellular mechanisms that underlie impaired brain function during phenylketonuria
(PKU), the most common biochemical cause of mental retardation in humans, remain …

Phenylketonuria (PKU), one of the most common inborn errors of amino acid metabolism, is
caused by mutations in the phenylalanine hydroxylase (PAH) gene (PAH). PKU has wide …

Phenylketonuria (PKU) is an autosomal recessive disorder characterized by a mutation in
the phenylalanine hydroxylase (PAH) gene. Untreated PKU can lead to mental retardation …

Phenylketonuria (PKU) is a metabolic disorder caused by mutations in the phenylalanine
hydroxylase (PAH) gene. After thalassemia, PKU is considered as the most common …

Background Phenylketonuria (PKU) screening is a public health measure taken to diagnose
and treat the patients with PKU to prevent severe neurological disorders in them. The …