Immunoinformatics and vaccine development: an overview

AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Subtractive proteomics to identify novel drug targets and reverse vaccinology for the development of chimeric vaccine against Acinetobacter baumannii

V Solanki, V Tiwari - Scientific reports, 2018 - nature.com
The emergence of drug-resistant Acinetobacter baumannii is the global health problem
associated with high mortality and morbidity. Therefore it is high time to find a suitable …

Serine Protease Autotransporters of the Enterobacteriaceae (SPATEs): Out and About and Chopping It Up

P Pokharel, H Habouria, H Bessaiah, CM Dozois - Microorganisms, 2019 - mdpi.com
Autotransporters are secreted proteins with multiple functions produced by a variety of Gram-
negative bacteria. In Enterobacteriaceae, a subgroup of these autotransporters are the …

Immunoinformatics Approach for Epitope‐Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus

UK Adhikari, M Tayebi… - Journal of immunology …, 2018 - Wiley Online Library
Oropouche virus (OROV) is an emerging pathogen which causes Oropouche fever and
meningitis in humans. Several outbreaks of OROV in South America, especially in Brazil …

Delineating the Immuno-Dominant Antigenic Vaccine Peptides Against gacS-Sensor Kinase in Acinetobacter baumannii: An in silico Investigational Approach

AS Smiline Girija - Frontiers in Microbiology, 2020 - frontiersin.org
Objectives To predict the novel vaccine peptide candidates against gacS protein involved
with the citrate utilization in the two-component system of A. baumannii-associated virulence …

[HTML][HTML] An integrated in silico based subtractive genomics and reverse vaccinology approach for the identification of novel vaccine candidate and chimeric vaccine …

K Khan, K Jalal, R Uddin - Genomics, 2022 - Elsevier
Salmonella typhi is notorious for causing enteric fever which is also known as typhoid fever.
It emerged as an extreme drug resistant strain that requires urgent attention to prevent its …

Design of novel viral attachment inhibitors of the spike glycoprotein (S) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) through virtual screening …

AR Oany, M Mia, T Pervin, M Junaid… - International journal of …, 2020 - Elsevier
To date, the global COVID-19 pandemic has been associated with 11.8 million cases and
over 545481 deaths. In this study, we have employed virtual screening approaches and …

Shigella Vaccines: The Continuing Unmet Challenge

T Lu, S Das, DR Howlader, WD Picking… - International Journal of …, 2024 - mdpi.com
Shigellosis is a severe gastrointestinal disease that annually affects approximately 270
million individuals globally. It has particularly high morbidity and mortality in low-income …

[HTML][HTML] In silico design of an epitope-based vaccine against choline binding protein A of Streptococcus pneumoniae

M Munia, S Mahmud, M Mohasin, KMK Kibria - Informatics in Medicine …, 2021 - Elsevier
Streptococcus pneumoniae (Pneumococcus) accounts for a major global health burden that
causes bacterial pneumonia, sepsis, otitis media, and meningitis. It is responsible for great …

Integrative systems biology approaches to identify potential biomarkers and pathways of cervical cancer

AR Oany, M Mia, T Pervin, SA Alyami… - Journal of personalized …, 2021 - mdpi.com
Nowadays, cervical cancer (CC) is treated as the leading cancer among women throughout
the world. Despite effective vaccination and improved surgery and treatment, CC retains its …