Malignant ascites (MA) accompanies a variety of abdominal and extra-abdominal tumors. It
is a primary cause of morbidity and raises several treatment challenges. MA has several …

Due to the significantly improved outcome and quality of life of patients with different tumor
entities after cytoreductive surgery (CRS) and HIPEC, there is an increasing number of …

The peritoneal metastatic route of cancer dissemination is shared by cancers of the ovary
and gastrointestinal tract. Once initiated, peritoneal metastasis typically proceeds rapidly in a …

OBJECTIVES: To compare survival data in platinum-sensitive recurrent ovarian cancer
patients submitted to secondary cytoreduction (SCR) plus hyperthermic intraperitoneal …

The management and the outcome of peritoneal metastases or recurrence from epithelial
ovarian cancer are presented. The biology and the diagnostic tools of EOC peritoneal …

Epithelial ovarian cancer (EOC) is the leading cause of death from gynecologic
malignancies and has a poor prognosis due to relatively unspecific early symptoms, and …

Background We analyze the efficacy of hyperthermic intraoperative intraperitoneal
chemotherapy (HIPEC) for microscopic residual disease in patients with stage IIIC/IV ovarian …

Purpose Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy
(HIPEC) are a novel curative treatment option for selected patients with peritoneal …

Please cite this paper as: Deraco M, Virzì S, Raspagliesi F, Iusco D, Puccio F, Macrì A,
Famulari C, Solazzo M, Bonomi S, Grassi A, Baratti D, Kusamura S. Secondary cytoreductive …

Cysteine cathepsins (CTSs) are involved in the degradation and remodeling of the
extracellular matrix and are associated with cellular transformation, differentiation, motility …