The apicoplast, a relict plastid found in most species of the phylum Apicomplexa, harbors the
ferredoxin redox system which supplies electrons to enzymes of various metabolic pathways …

Iron–sulfur [Fe–S] clusters are one of the most ancient, ubiquitous, structurally and
functionally versatile natural biosynthetic prosthetic groups required by various proteins …

Ferredoxin (Fd) and ferredoxin-NADP+ reductase (FNR) form a redox system that is
hypothesized to play a central role in the maintenance and function of the apicoplast …

Drug resistance against antimalarials is rendering them increasingly ineffective and so there
is a need for the development of new antimalarials. To discover new antimalarial …

The Plasmodium parasites belong to the phylum Apicomplexa, and harbor a vital multi
membrane organelle known as apicoplast (McFadden et al., 1996; Foth and McFadden …

Abstract Mutation of Asp97Tyr in the C-terminal region of ferredoxin (PfFd) in the apicoplast
of malaria parasites was recently reported to be strongly related to the parasite's resistance …

FNR and ferredoxin constitute a redox cascade, which provides reducing power in the
plastid of malaria parasites. Recently, mutation of ferredoxin (D97Y) was reported to be …

Biosynthesis of isoprenoids (MEP Pathway) in apicoplast has an important role during the
erythrocytic stages of Plasmodium, as it is the sole pathway to provide the major isoprene …

The discovery of a relict plastid, also known as an apicoplast (apicomplexan plastid), that
houses housekeeping processes and metabolic pathways critical to Plasmodium parasites' …

The malaria parasite (Plasmodium falciparum) possesses a plastid-derived, essential
organelle called the apicoplast, which contains a redox system comprising plant-type …