In eukaryotes, the translation initiation codon is generally identified by the scanning
mechanism, wherein every triplet in the messenger RNA leader is inspected for …

Translation initiation in eukaryotes is a highly regulated and complex stage of gene
expression. It requires the action of at least 12 initiation factors, many of which are known to …

Elevated protein synthesis is an important feature of many cancer cells and often arises as a
consequence of increased signaling flux channeled to eukaryotic initiation factor 4F (eIF4F) …

Translation initiation in eukaryotes is a complex and highly regulated process requiring the
action of at least 12 protein factors. The pathway is distinguished by the formation of a pre …

The Y‐box binding protein 1 (YB‐1, YBX1) is a member of the family of DNA‐and RNA‐
binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into …

Certain chemical modifications confer increased stability and low immunogenicity to in vitro
transcribed mRNAs, thereby facilitating expression of therapeutically important proteins …

The correct translation of mRNA depends critically on the ability to initiate at the right AUG
codon. For most mRNAs in eukaryotic cells, this is accomplished by the scanning …

This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …

The 5′ mRNA cap structure is essential for efficient gene expression from yeast to human. It
plays a critical role in all aspects of the life cycle of an mRNA molecule. Capping occurs co …

Abstract Stress-induced angiogenin (ANG)-mediated tRNA cleavage promotes a cascade of
cellular events that starts with production of tRNA-derived stress-induced RNAs (tiRNAs) …