Revisiting tramadol: a multi-modal agent for pain management

A Barakat - CNS drugs, 2019 - Springer
Tramadol—an atypical opioid analgesic—has a unique pharmacokinetic and
pharmacodynamic profile, with opioidergic, noradrenergic, and serotonergic actions …

The efficacy and clinical safety of various analgesic combinations for post-operative pain after third molar surgery: a systematic review and meta-analysis

AHY Au, SW Choi, CW Cheung, YY Leung - PLoS One, 2015 - journals.plos.org
Objectives To run a systematic review and meta-analysis of randomized clinical trials aiming
to answer the clinical question “which analgesic combination and dosage is potentially the …

Peripheral painful traumatic trigeminal neuropathies

R Benoliel, J Kahn, E Eliav - Oral diseases, 2012 - Wiley Online Library
Oral Diseases (2012) 18, 317–332 The aim of this article is to review the clinical,
pathophysiological, and therapeutic aspects of traumatically induced trigeminal nerve pain …

Effect of pre-emptive analgesia on clinical parameters and tissue levels of TNF-α and IL-1β in third molar surgery: a triple-blind, randomized, placebo-controlled study

AFM Albuquerque, CSR Fonteles, DR Do Val… - International journal of …, 2017 - Elsevier
This study aimed to evaluate whether pre-emptive analgesia modifies the tissue expression
of tumour necrosis factor alpha (TNF-α) and interleukin 1 beta (IL-1β), and whether there is …

Comparative study of intravenous Tramadol versus Ketorolac for preventing postoperative pain after third molar surgery–A prospective randomized study

P Gopalraju, RM Lalitha, K Prasad… - Journal of Cranio …, 2014 - Elsevier
The aim of this comparative, prospective, randomized, controlled study was to evaluate two
different regimens of analgesics: a preoperative intravenous dose of either Tramadol or …

Evaluation of the paw withdrawal latency for the comparison between tramadol and butorphanol administered locally, in the plantar surface of rat, preliminary study

C Interlandi, F Leonardi, F Spadola, GL Costa - PLoS One, 2021 - journals.plos.org
The aim of the study was to evaluate the analgesic efficacy of tramadol compared to
butorphanol administered locally in ventral surface of the hind paw of rats. Prospective …

A triple-blind randomized clinical trial of different associations between dexamethasone and non-steroids anti-inflammatories for preemptive action in third molar …

GAC Momesso, GA Grossi-Oliveira, WPP Silva… - Scientific Reports, 2021 - nature.com
The aim of this study is to evaluate the preemptive analgesic effects of dexamethasone
(DEX) alone or combined with non-steroidal anti-inflammatory drugs (NSAIDs) in third molar …

Efficacy and safety of parenteral and local application of tramadol in mandibular third molar extraction: a qualitative systematic review of current evidence

MM Gounari, G Tsaousi, L Zouloumis… - Oral and maxillofacial …, 2024 - Springer
Purpose To assess the efficacy and safety of perioperative parenteral administration or
submucosal infiltration of tramadol for perioperative pain control on the basis of pain …

[HTML][HTML] Comparison of the analgesic efficacy of oral ketorolac versus intramuscular tramadol after third molar surgery: A parallel, double-blind, randomized, placebo …

MA Isiordia-Espinoza, A Pozos-Guillen… - … oral, patologia oral y …, 2016 - ncbi.nlm.nih.gov
Background Preemptive analgesia is considered an alternative for treating the postsurgical
pain of third molar removal. The aim of this study was to evaluate the preemptive analgesic …

Clinical and radiographic characteristics as predictive factors of swelling and trismus after mandibular third molar surgery: a longitudinal approach

JM Pérez-González… - Pain Research and …, 2018 - Wiley Online Library
Introduction. Factors that contribute to swelling and trismus are complex, and they are
originated by surgical trauma. The aim of the present study was to determine whether …