Metabolic reprogramming in lung cancer and its clinical implication

Q Huang, L Fan, M Gong, J Ren, C Chen… - Frontiers in …, 2024 - frontiersin.org
Lung cancer has posed a significant challenge to global health, and related study has been
a hot topic in oncology. This article focuses on metabolic reprogramming of lung cancer …

PTBP1 crotonylation promotes colorectal cancer progression through alternative splicing-mediated upregulation of the PKM2 gene

JY Hou, XL Wang, HJ Chang, XX Wang, SL Hao… - Journal of Translational …, 2024 - Springer
Background Aerobic glycolysis is a tumor cell phenotype and a hallmark in cancer research.
The alternative splicing of the pyruvate kinase M (PKM) gene regulates the expressions of …

De-SUMO1ylated hexokinase 1 selectively degraded by ubiquitin-proteasome pathway promotes boar sperm capacitation in vitro

S Yao, Q Xu, Y Lv, Y Zhang, H Li, J Zhang, Z Yao… - Animal Reproduction …, 2025 - Elsevier
This study investigates the effect of de-SUMOylated hexokinase 1 (HK1) degradation on
sperm capacitation in vitro. Sperm from adult Landrace pigs was divided into three groups …

[PDF][PDF] Targeting the PRMT1-cGAS-STING signaling pathway to enhance the anti-tumor therapeutic efficacy

D Huang, AH Rezaeian, J Wang, Y Qi, H Chen… - Journal of …, 2024 - researchgate.net
Activating innate immune signaling in tumor cells to enhance anti-tumor immunity and
increase T cellmediated killing is the core objective of tumor immunotherapy. PRMT1, one of …

[引用][C] NAT10 primes a post-transcriptional repertoire essential for the maintenance of spermatogonial homeostasis

X Zhu, C Xu, X Jiang, J Zou, W Li, X Xing, X Gao, J Lei… - Science Bulletin, 2025 - Elsevier