Adult neurogenesis, the birth of new neurons in the mature brain, has attracted considerable
attention in the last decade. One of the earliest identified and most profound factors that …

Dclk1-expressing tuft cells constitute a unique intestinal epithelial lineage that is distinct from
enterocytes, Paneth cells, goblet cells, and enteroendocrine cells. Tuft cells express taste …

Abstract Rationale: Doublecortin-like kinase 1 (DCLK1) is a serine/threonine kinase that
selectively marks cancer stem-like cells (CSCs) and promotes malignant progression in …

Glucocorticoids (GCs) secreted after stress reduce adult hippocampal neurogenesis, a
process that has been implicated in cognitive aspects of psychopathology, amongst others …

Cortical tubers in patients with tuberous sclerosis complex are associated with disabling
neurological manifestations, including intractable epilepsy. While these malformations are …

Lissencephaly is a rare brain malformation for which our understanding remains limited due
to the absence of suitable animal models that accurately represent human phenotypes …

Neurons in the central nervous system lose their intrinsic capacity for axon regeneration as
they mature, and it is widely hypothesized that changes in gene expression are responsible …

Type 1 diabetes is a common metabolic disorder accompanied by an increased secretion of
glucocorticoids and cognitive deficits. Chronic excess of glucocorticoids per se can evoke …

Dendritic morphogenesis and formation of synapses at appropriate dendritic locations are
essential for the establishment of proper neuronal connectivity. Recent imaging studies …

Abstract Doublecortin-like kinase 1 (DCLK1), a microtubule-associated protein kinase, is
involved in neurogenesis, and its levels are elevated in various human cancers. Recent …