Despite the development of targeted therapy, drug resistance remains a primary hindrance
to curative treatment of various cancers. Among several novel approaches to overcome drug …

Abstract Human AlkB homolog H5 (ALKBH5) is a primary m6A demethylase, which is
dysregulated and acts as a biological and pharmacological role in human cancers or non …

The intestinal invasion of pathogenic microorganisms can have serious health
consequences. Recent evidence has shown that the N 6-methyladenosine (m6A) mRNA …

Abstract N6-methyladenosine (m6A) is one of the most important epigenetic regulation of
RNAs, such as lncRNAs. However, the underlying regulatory mechanism of m6A in diabetic …

Abstract N6-methyladenosine (m6A) is the most prevalent internal modification in
mammalian mRNAs and methyltransferase-like 3 (METTL3) is a vital methyltransferase in …

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in China. N6‑
methyladenosine (m6A) plays an important role in posttranscriptional gene regulation …

N6 methyladenosine (m6A) RNA methylation regulators play an important role in the
development of tumors. However, their function in esophageal cancer (EC) has not been …

Ovarian cancer is the deadliest gynaecologic malignancy, and the five-year survival rate of
patients is less than 35% worldwide. Cancer stem cells (CSCs) are a population of cells with …

Chemical modifications play an important role in modifying and regulating the functions of
coding and noncoding RNAs. Noncoding RNAs mainly include microRNAs (miRNAs), long …

Abstract N6-methyladenosine (m6A) acts as the most common mRNA modification in
mammal cells. Fat Mass and Obesity-associated protein (FTO) is the firstly identified …