Venom and poison peptides are powerful biological weapons and have proven immense
pharmacological potential because of their high binding affinity to a wide range of molecular …

Nature's way for bioactive peptides is to provide them with several related functions and the
ability to cooperate in performing their job. Natural cell-penetrating peptides (CPP), such as …

We have developed a new concept for reversible peptide stapling that involves
macrocyclization between two amino groups and decyclization promoted via dual 1, 4 …

Nonselective toxicity of antimicrobial peptides (AMPs) needs to be solved urgently for their
application. Temporin-PE (T-PE, FLPIVAKLLSGLL-NH2), an AMP extracted from skin …

The pharmacodynamic and pharmacokinetic properties of bioactive peptides can be
modulated by introducing conformational constraints such as intramolecular …

Temporins are one of the largest families of antimicrobial peptides with both anti-
inflammatory and antimicrobial activity. Herein, for a panel of cyclic temporin L isoform …

The demand for new molecules to counter bacterial resistance to antibiotics and tumor cell
resistance is increasingly pressing. The Mediterranean seagrass Posidonia oceanica is …

Objectives This study tried to achieve active targeting of Muc1 in cancer; the surface of
PEGylated liposomal doxorubicin (PLD/Doxil®) was decorated with FA12 peptide. Methods …

The increasing resistance of fungi to conventional antifungal drugs has prompted worldwide
the search for new compounds. In this work, we investigated the antifungal properties of …

Antimicrobial peptides (AMPs) constitute part of a broad range of bioactive compounds
present on diverse organisms, including frogs. Peptides, produced in the granular glands of …