This article aims to promote integration of angiogenesis-related models, both integration of
the work described herein and many other existing and future models. Integration of …

Whole Brain Emulation: A Roadmap Page 1 Whole Brain Emulation A Roadmap (2008)
Technical Report #2008-3 Anders Sandberg* Nick Bostrom Future of Humanity Institute …

The goal of location proteomics is the systematic and comprehensive study of protein
subcellular location. We have previously developed automated, quantitative methods to …

Background Gene expression microarray and other multiplex data hold promise for
addressing the challenges of cellular complexity, refined diagnoses and the discovery of …

Microbial activity governs elemental cycling and the transformation of many anthropogenic
substances in aqueous environments. Through the development of a dynamic cell model of …

Transcriptional regulatory network (TRN) discovery from one method (eg microarray
analysis, gene ontology, phylogenic similarity) does not seem feasible due to lack of …

This work focuses on the experimental analysis of the time-course of protein expression in a
cell-free system, in conjunction with the development of a computational model, denoted as …

It is hypothesized that the many human cell types corresponding to multiple states is
supported by an underlying nonlinear dynamical system (NDS) of transcriptional regulatory …

Glycolysis in Trypanosoma brucei was modeled using a reaction transport simulator and
tested for possible complex dynamics. The glycolytic model is multi-compartmentalized and …

In order to account for the multi-phasic dynamics of photopigment regeneration in human
rods, we developed a new model of the retinoid cycle. We first examined the relative roles of …