Dietary regulation of oxidative stress in chronic metabolic diseases

S Jiang, H Liu, C Li - Foods, 2021 - mdpi.com
Oxidative stress is a status of imbalance between oxidants and antioxidants, resulting in
molecular damage and interruption of redox signaling in an organism. Indeed, oxidative …

Wound chronicity, impaired immunity and infection in diabetic patients

N Rodríguez-Rodríguez, I Martínez-Jiménez… - MEDICC …, 2022 - SciELO Public Health
BACKGROUND Diabetic foot ulcers are a common diabetic complication leading to
alarming figures of amputation, disability, and early mortality. The diabetic glucooxidative …

NOS inhibition reverses TLR2-induced chondrocyte dysfunction and attenuates age-related osteoarthritis

P Shen, S Serve, P Wu, X Liu, Y Dai… - Proceedings of the …, 2023 - National Acad Sciences
Osteoarthritis (OA) is a joint disease featuring cartilage breakdown and chronic pain.
Although age and joint trauma are prominently associated with OA occurrence, the trigger …

[HTML][HTML] A comprehensive map of microbial biomarkers along the gastrointestinal tract for celiac disease patients

JE Arcila-Galvis, V Loria-Kohen… - Frontiers in …, 2022 - frontiersin.org
Dysbiosis of the microbiome has been related to Celiac disease (CeD) progress, an
autoimmune disease characterized by gluten intolerance developed in genetically …

Epigenetic regulation of inflammation: The metabolomics connection

S Rath, YM Hawsawi, F Alzahrani, MI Khan - Seminars in Cell & …, 2022 - Elsevier
Epigenetic factors are considered the regulator of complex machinery behind inflammatory
disorders and significantly contributed to the expression of inflammation-associated genes …

Statin use in relation to COVID-19 and other respiratory infections: Muscle and other considerations

BA Golomb, JH Han, PH Langsjoen… - Journal of Clinical …, 2023 - mdpi.com
Statins have been widely advocated for use in COVID-19 based on large favorable
observational associations buttressed by theoretical expected benefits. However, past …

[HTML][HTML] Transcription Factors Interplay Orchestrates the Immune-Metabolic Response of Leishmania Infected Macrophages

H Bichiou, C Bouabid, I Rabhi… - Frontiers in Cellular and …, 2021 - frontiersin.org
Leishmaniasis is a group of heterogenous diseases considered as an important public
health problem in several countries. This neglected disease is caused by over 20 parasite …

Morphological assessment and biomarkers of low-grade, chronic intestinal inflammation in production animals

I Soares, BL Belote, E Santin, GC Dal Pont, MH Kogut - Animals, 2022 - mdpi.com
Simple Summary Production animals are continuously exposed to environmental and
dietary factors that might induce a state of low-grade, chronic intestinal inflammation. This …

A comprehensive analysis based on histopathology, metabolomics and transcriptomics reveals molecular regulatory mechanisms of the red claw crayfish (Cherax …

D Chen, C Wang, L Guo, W Mo, Y Xin, H Cao, C Mu… - Aquaculture, 2022 - Elsevier
The maintenance of homeostasis is central for the survival of organisms under exposure to
various types of stress, toxicants, and pathogens, and small metabolites often play key roles …

[HTML][HTML] Human tear metabolites associated with nucleoside-signalling pathways in bacterial keratitis

GS Shrestha, AK Vijay, F Stapleton, A White… - Experimental Eye …, 2023 - Elsevier
Objective The study aimed to profile and quantify tear metabolites associated with bacterial
keratitis using both untargeted and targeted metabolomic platforms. Methods Untargeted …