ED Herzog - Nature Reviews Neuroscience, 2007 - nature.com
Biological pacemakers dictate our daily schedules in physiology and behaviour. The molecules, cells and networks that underlie these circadian rhythms can now be monitored …
Covalent modification of histones is important in regulating chromatin dynamics and transcription,. One example of such modification is ubiquitination, which mainly occurs on …
D Stoleru, Y Peng, J Agosto, M Rosbash - Nature, 2004 - nature.com
Daily rhythms of physiology and behaviour are precisely timed by an endogenous circadian clock,. These include separate bouts of morning and evening activity, characteristic of …
B Grima, E Chélot, R Xia, F Rouyer - Nature, 2004 - nature.com
In Drosophila, a 'clock'situated in the brain controls circadian rhythms of locomotor activity. This clock relies on several groups of neurons that express the Period (PER) protein …
Circadian rhythms influence most of our life activities, notably getting up and going to sleep every day. The new edition of this book delves into the mechanisms surrounding how these …
In Drosophila, molecular clocks control circadian rhythmic behavior through a network of~ 150 pacemaker neurons. To explain how the network's neuronal properties encode time, we …
N Peschel, C Helfrich-Förster - FEBS letters, 2011 - Elsevier
Nowadays humans mainly rely on external, unnatural clocks such as of cell phones and alarm clocks–driven by circuit boards and electricity. Nevertheless, our body is under the …
Coupling of autonomous cellular oscillators is an essential aspect of circadian clock function but little is known about its circuit requirements. Functional ablation of the pigment …
Molecular genetics has revealed the identities of several components of the fundamental circadian molecular oscillator—an evolutionarily conserved molecular mechanism of …