microRNA strand selection: Unwinding the rules

JC Medley, G Panzade… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
Abstract microRNAs (miRNAs) play a central role in the regulation of gene expression by
targeting specific mRNAs for degradation or translational repression. Each miRNA is post …

Cervical cancer, papillomavirus, and miRNA dysfunction

EG Bañuelos-Villegas, MF Pérez-yPérez… - Frontiers in Molecular …, 2021 - frontiersin.org
Cervical cancer is the leading cause of death by cancer in women from developing
countries. Persistent infection with high-risk human papillomavirus (HPV) types 16 and 18 is …

LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR

Y Xu, H Fang, Q Xu, C Xu, L Yang, C Huang - Cell Cycle, 2020 - Taylor & Francis
Long noncoding RNA GAS5 is down-regulated in cardiomyocytes in diabetic
cardiomyopathy (DCM). Here, we studied the involvement of GAS5 in DCM by analyzing its …

MicroRNA-34 family in cancers: role, mechanism, and therapeutic potential

J Fu, S Imani, MY Wu, RC Wu - Cancers, 2023 - mdpi.com
Simple Summary The dysregulation of the miR-34 family has been shown to play an
important role in tumorigenesis and cancer progression. In this review, we summarized the …

p53/MicroRNA-34 axis in cancer and beyond

W Pan, B Chai, L Li, Z Lu, Z Ma - Heliyon, 2023 - cell.com
Cancer is serious endangers human life. After a long period of research and accumulation,
people's understanding of cancer and the corresponding treatment methods are constantly …

microRNA-34 family: From mechanism to potential applications

C Wang, Q Jia, X Guo, K Li, W Chen, Q Shen… - … International Journal of …, 2022 - Elsevier
Abstract microRNA-34, a highly conserved microRNA in evolution, is of great interest in
recent years. miR-34 regulates multiple targets and performed many functions in cells, such …

Cancer-associated fibroblast exosome LINC00355 promotes epithelial-mesenchymal transition and chemoresistance in colorectal cancer through the miR-34b-5p …

JH Hu, HN Tang, YH Wang - Cancer Gene Therapy, 2024 - nature.com
This study was designed to investigate the role and mechanism of cancer-associated
fibroblasts (CAFs)-derived exosomes (CAFs-exo) in metastatic and chemoresistant …

MiR‐34b‐3p represses cell proliferation, cell cycle progression and cell apoptosis in non‐small‐cell lung cancer (NSCLC) by targeting CDK4

H Feng, F Ge, L Du, Z Zhang… - Journal of Cellular and …, 2019 - Wiley Online Library
Lung cancer is the most common incident cancer, with a high mortality worldwide, and non‐
small‐cell lung cancer (NSCLC) accounts for approximately 85% of cases. Numerous …

miR-146a, miR-221, and miR-155 are involved in inflammatory immune response in severe COVID-19 patients

N Gaytán-Pacheco, A Ibáñez-Salazar… - Diagnostics, 2022 - mdpi.com
COVID-19 infection triggered a global public health crisis during the 2020–2022 period, and
it is still evolving. This highly transmissible respiratory disease can cause mild symptoms up …

The potential role of miRNAs and regulation of their expression in the development of mare endometrial fibrosis

A Wójtowicz, T Molcan, K Lukasik, E Żebrowska… - Scientific Reports, 2023 - nature.com
Mare endometrial fibrosis (endometrosis), is one of the main causes of equine infertility.
Despite the high prevalence, both ethology, pathogenesis and the nature of its progression …