Modelling of bone fracture and strength at different length scales: a review

FA Sabet, A Raeisi Najafi, E Hamed… - Interface …, 2016 - royalsocietypublishing.org
In this paper, we review analytical and computational models of bone fracture and strength.
Bone fracture is a complex phenomenon due to the composite, inhomogeneous and …

Advanced modeling methods—applications to bone fracture mechanics

A Ural - Current Osteoporosis Reports, 2020 - Springer
Abstract Purpose of Review The goal of this review is to summarize recent advances in
modeling of bone fracture using fracture mechanics–based approaches at multiple length …

Identifying novel clinical surrogates to assess human bone fracture toughness

M Granke, AJ Makowski, S Uppuganti… - Journal of Bone and …, 2015 - academic.oup.com
Fracture risk does not solely depend on strength but also on fracture toughness; ie, the
ability of bone material to resist crack initiation and propagation. Because resistance to crack …

An integrated experimental-computational framework to assess the influence of microstructure and material properties on fracture toughness in clinical specimens of …

A Demirtas, EA Taylor, B Gludovatz, RO Ritchie… - Journal of the …, 2023 - Elsevier
Microstructural and compositional changes that occur due to aging, pathological conditions,
or pharmacological treatments alter cortical bone fracture resistance. However, the relative …

Fracture behavior of human cortical bone: Role of advanced glycation end-products and microstructural features

E Maghami, TO Josephson, JP Moore, T Rezaee… - Journal of …, 2021 - Elsevier
Diabetes is associated with increased fracture risk in human bone, especially in the elderly
population. In the present study, we investigate how simulated advanced glycation end …

Computational study of the mechanical influence of lacunae and perilacunar zones in cortical bone microcracking

TO Josephson, JP Moore, E Maghami… - Journal of the …, 2022 - Elsevier
The mechanical behavior of cortical bone is influenced by microstructural components such
as osteons, Haversian canals, and osteocyte lacunae that arise from biological remodeling …

Effect of ageing on microstructure and fracture behavior of cortical bone as determined by experiment and Extended Finite Element Method (XFEM)

RN Yadav, P Uniyal, P Sihota, S Kumar… - Medical Engineering & …, 2021 - Elsevier
Bone fracture is a severe health concern; therefore, understanding the causes of bone
fracture are crucial. This paper investigates the microstructure and fracture behaviour of …

Damage analysis of human cortical bone under compressive and tensile loadings

E Maghami, JP Moore, TO Josephson… - Computer methods in …, 2022 - Taylor & Francis
Developing advanced fracture tools can increase the understanding of crack growth
trajectories in human cortical bone. The present study investigates fracture micromechanics …

Calculation of the critical energy release rate Gc of the cement line in cortical bone combining experimental tests and finite element models

E Giner, R Belda, C Arango, A Vercher-Martínez… - Engineering fracture …, 2017 - Elsevier
In this work, a procedure is proposed to estimate the critical energy release rate G c of the so-
called cement line in cortical bone tissue. Due to the difficulty of direct experimental …

Hierarchical perspective of bone toughness–from molecules to fracture

A Ural, D Vashishth - International Materials Reviews, 2014 - journals.sagepub.com
Osteoporotic and age-related fractures are a significant public health problem. The current
standard of osteoporosis assessment via bone mineral density has been shown to be …