Sorting out sorting nexins functions in the nervous system in health and disease

N Vieira, T Rito, M Correia-Neves, N Sousa - Molecular neurobiology, 2021 - Springer
Endocytosis is a fundamental process that controls protein/lipid composition of the plasma
membrane, thereby shaping cellular metabolism, sensing, adhesion, signaling, and nutrient …

Structural predictions of the SNX-RGS proteins suggest they belong to a new class of lipid transfer proteins

B Paul, S Weeratunga, VA Tillu, H Hariri… - Frontiers in cell and …, 2022 - frontiersin.org
Recent advances in protein structure prediction using machine learning such as AlphaFold2
and RosettaFold presage a revolution in structural biology. Genome-wide predictions of …

TRAPPC9: Novel insights into its trafficking and signaling pathways in health and disease

T Mbimba, NJ Hussein… - … Journal of Molecular …, 2018 - spandidos-publications.com
Trafficking protein particle complex 9 (TRAPPC9) is a protein subunit of the transport protein
particle II (TRAPPII), which has been reported to be important in the trafficking of cargo from …

Systematic prediction of FFAT motifs across eukaryote proteomes identifies nucleolar and eisosome proteins with the predicted capacity to form bridges to the …

JA Slee, TP Levine - Contact, 2019 - journals.sagepub.com
The endoplasmic reticulum (ER), the most pervasive organelle, exchanges information and
material with many other organelles, but the extent of its interorganelle connections and the …

[HTML][HTML] DNA methylation-regulated SNX20 overexpression correlates with poor prognosis, immune cell infiltration, and low-grade glioma progression

X Chen, X Jiang, H Wang, C Wang, C Wang… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
We revealed that SNX20 was up-regulated in LGG, and its higher expression was
associated with adverse clinical outcomes and poor clinical characteristics, including WHO …

SNX20AR/MiRNA-301a-3p/SNX20 axis associated with cell proliferation and immune infiltration in lung adenocarcinoma

Y Yuan, X Jiang, L Tang, J Wang, Q Liu… - Frontiers in Molecular …, 2021 - frontiersin.org
Lung cancer is the most common tumor with severe morbidity and high mortality. Increasing
evidence has demonstrated that SNX20 plays crucial roles in the progression of human …

HLB1 is a tetratricopeptide repeat domain-containing protein that operates at the intersection of the exocytic and endocytic pathways at the TGN/EE in Arabidopsis

JA Sparks, T Kwon, L Renna, F Liao, F Brandizzi… - The Plant …, 2016 - academic.oup.com
The endomembrane system plays essential roles in plant development, but the proteome
responsible for its function and organization remains largely uncharacterized in plants. Here …

Regulation of the phosphoinositide code by phosphorylation of membrane readers

TA Kervin, M Overduin - Cells, 2021 - mdpi.com
The genetic code that dictates how nucleic acids are translated into proteins is well known,
however, the code through which proteins recognize membranes remains mysterious. In …

Phosphoinositide recognition sites are blocked by metabolite attachment

TA Kervin, BC Wiseman, M Overduin - Frontiers in Cell and …, 2021 - frontiersin.org
Membrane readers take part in trafficking and signaling processes by localizing proteins to
organelle surfaces and transducing molecular information. They accomplish this by …

Significance of NatB-mediated N-terminal acetylation of auxin biosynthetic enzymes in maintaining auxin homeostasis in Arabidopsis thaliana

HQ Liu, ZX Pu, DW Di, YJ Zou, YM Guo… - Communications …, 2022 - nature.com
Abstract The auxin IAA (Indole-3-acetic acid) plays key roles in regulating plant growth and
development, which depends on an intricate homeostasis that is determined by the balance …