Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight

JK Kim, BT Tierney, EG Overbey, E Dantas… - Nature …, 2024 - nature.com
Spaceflight induces an immune response in astronauts. To better characterize this effect, we
generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data …

Telomeric RNA (TERRA) increases in response to spaceflight and high-altitude climbing

TM Al-Turki, DG Maranon, CB Nelson… - Communications …, 2024 - nature.com
Telomeres are repetitive nucleoprotein complexes at chromosomal termini essential for
maintaining genome stability. Telomeric RNA, or TERRA, is a previously presumed long …

Targeted proteomic analysis of dry blood spot samples collected during long-term spaceflights

A Kononikhin, I Larina, A Brzhozovskiy, S Semenov… - 2024 - researchsquare.com
The molecular mechanisms of organismal adaptation to spaceflight (SF) conditions are not
fully investigated and remain relevant for study. Newly emerging multi-omics technologies …