The human genome is organized into multiple structural layers, ranging from chromosome
territories to progressively smaller substructures, such as topologically associating domains …

The glucocorticoid receptor (GR) is a bona fide ligand‐regulated transcription factor. Cloned
in the 80s, the GR has become one of the best‐studied and clinically most relevant members …

Simultaneous measurements of transcriptomic and epigenomic profiles in the same
individual cells provide an unprecedented opportunity to understand cell fates. However …

The glucocorticoid receptor (GR) regulates gene expression, governing aspects of
homeostasis, but is also involved in cancer. Pharmacological GR activation is frequently …

The glucocorticoid receptor (GR) is a hormone-inducible transcription factor involved in
metabolic and anti-inflammatory gene expression responses. To investigate what controls …

A widely regarded model for glucocorticoid receptor (GR) action postulates that dimeric
binding to DNA regulates unfavorable metabolic pathways while monomeric receptor …

The transcription factor MYC is overexpressed in most cancers, where it drives multiple
hallmarks of cancer progression. MYC is known to promote oncogenic transcription by …

The glucocorticoid receptor (GR) has been shown to be important for mediating cellular
responses to stress and circulating glucocorticoids. Ligand-dependent transcriptional …

Glucocorticoids (GCs) exert potent anti-inflammatory effects in immune cells through the
glucocorticoid receptor (GR). Dendritic cells (DCs), central actors for coordinating immune …

Glucocorticoid receptor (GR) is a key homeostatic regulator involved in governing immune
response, neuro-integration, metabolism and lung function. In conjunction with its pivotal …