Nature of interactions of amino acids with bare magnetite nanoparticles

SP Schwaminger, PF García, GK Merck… - The Journal of …, 2015 - ACS Publications
Owing to their chemical and magnetic properties, magnetite nanoparticles are an interesting
adsorbing material for biomolecules. The understanding of the interactions of simple …

Mitochondrial targets for pharmacological intervention in human disease

RH Malty, M Jessulat, K Jin, G Musso… - Journal of proteome …, 2015 - ACS Publications
Over the past several years, mitochondrial dysfunction has been linked to an increasing
number of human illnesses, making mitochondrial proteins (MPs) an ever more appealing …

Peptides and peptide analogs to inhibit protein-protein interactions

D Helmer, K Schmitz - … Compounds: Prediction, Selection and Activity of …, 2016 - Springer
Protein-protein interactions are governed by relatively few amino acid residues at the
binding interface. Peptides derived from these protein regions may serve as mimics of one of …

Solution NMR characterization of WT CXCL 8 monomer and dimer binding to CXCR 1 N‐terminal domain

PRB Joseph, K Rajarathnam - Protein Science, 2015 - Wiley Online Library
Chemokine CXCL8 and its receptor CXCR1 are key mediators in combating infection and
have also been implicated in the pathophysiology of various diseases including chronic …

Structural basis of native CXCL7 monomer binding to CXCR2 receptor N-domain and glycosaminoglycan heparin

AJ Brown, KM Sepuru, K Rajarathnam - International journal of molecular …, 2017 - mdpi.com
CXCL7, a chemokine highly expressed in platelets, orchestrates neutrophil recruitment
during thrombosis and related pathophysiological processes by interacting with CXCR2 …

Engineered anti-inflammatory peptides inspired by mapping an evasin–chemokine interaction

B Darlot, JRO Eaton, L Geis-Asteggiante… - Journal of Biological …, 2020 - ASBMB
Chemokines mediate leukocyte migration and homeostasis and are key targets in
inflammatory diseases including atherosclerosis, cytokine storm, and chronic autoimmune …

Macrocyclization enhances affinity of chemokine‐binding peptoids

K Brahm, JS Wack, S Eckes, V Engemann… - …, 2019 - Wiley Online Library
Peptoids that bind to protein targets can be selected from one‐bead‐one‐compound
libraries. Macrocyclization has been often used to increase conformational rigidity and …

A computational study of the chemokine receptor CXCR1 bound with interleukin-8

Y Wang, CS Lupala, T Wang, X Li, JH Yun… - Chinese …, 2018 - iopscience.iop.org
CXCR1 is a G-protein coupled receptor, transducing signals from chemokines, in particular
the interleukin-8 (IL8) molecules. This study combines homology modeling and molecular …

Design of modulatory peptides against chemokines

B Darlot - 2021 - ora.ox.ac.uk
Chemotactic cytokines or chemokines are small signalling proteins responsible for the
recruitment of leukocytes to sites of inflammation. Although, chemokines are critical to …

Modulation of complement activity

MD Hoarty, KA Dhamnaskar, D Elbaum… - US Patent …, 2024 - Google Patents
US11965040B2 - Modulation of complement activity - Google Patents US11965040B2 -
Modulation of complement activity - Google Patents Modulation of complement activity Info …