Papillomavirus immune evasion strategies target the infected cell and the local immune system
Persistent infection with human papillomavirus (HPV) initiates~ 5% of all human cancers,
and particularly cervical and oropharyngeal cancers. HPV vaccines prevent HPV infection …
and particularly cervical and oropharyngeal cancers. HPV vaccines prevent HPV infection …
Role of innate immunity against human papillomavirus (HPV) infections and effect of adjuvants in promoting specific immune response
A Amador-Molina, JF Hernández-Valencia, E Lamoyi… - Viruses, 2013 - mdpi.com
During the early stages of human papillomavirus (HPV) infections, the innate immune
system creates a pro-inflammatory microenvironment by recruiting innate immune cells to …
system creates a pro-inflammatory microenvironment by recruiting innate immune cells to …
New insights into IDO biology in bacterial and viral infections
SV Schmidt, JL Schultze - Frontiers in immunology, 2014 - frontiersin.org
Initially, indoleamine-2, 3-dioxygenase (IDO) has been introduced as a bactericidal effector
mechanism and has been linked to T-cell immunosuppression and tolerance. In recent …
mechanism and has been linked to T-cell immunosuppression and tolerance. In recent …
[HTML][HTML] Modulation of antigen presenting cell functions during chronic HPV infection
High-risk human papillomaviruses (HR-HPV) infect basal keratinocytes, where in some
individuals they evade host immune responses and persist. Persistent HR-HPV infection of …
individuals they evade host immune responses and persist. Persistent HR-HPV infection of …
IL-17 suppresses immune effector functions in human papillomavirus-associated epithelial hyperplasia
Persistent infection with high-risk human papillomaviruses (HPV) causes epithelial
hyperplasia that can progress to cancer and is thought to depend on immunosuppressive …
hyperplasia that can progress to cancer and is thought to depend on immunosuppressive …
DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7 …
J Chandra, JL Dutton, B Li, WP Woo, Y Xu… - Journal of …, 2017 - journals.lww.com
We have previously shown that a novel DNA vaccine technology of codon optimization and
the addition of ubiquitin sequences enhanced immunogenicity of a herpes simplex virus 2 …
the addition of ubiquitin sequences enhanced immunogenicity of a herpes simplex virus 2 …
HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2-and CCL5-mediated recruitment of mast cells
Human Papillomavirus (HPV) 16 E7 protein promotes the transformation of HPV infected
epithelium to malignancy. Here, we use a murine model in which the E7 protein of HPV16 is …
epithelium to malignancy. Here, we use a murine model in which the E7 protein of HPV16 is …
[HTML][HTML] Indoleamine 2, 3-dioxygenase activity contributes to local immune suppression in the skin expressing human papillomavirus oncoprotein e7
Chronic infection of anogenital epithelium with human papillomavirus (HPV) promotes
development of cancer. Many pathogens evoke immunosuppressive mechanisms to enable …
development of cancer. Many pathogens evoke immunosuppressive mechanisms to enable …
Comparative immune phenotypic analysis of cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in immune-competent individuals: proportional …
A Freeman, JA Bridge, P Maruthayanar, NH Overgaard… - PloS one, 2014 - journals.plos.org
Squamous Cell Carcinoma (SCC) is a type of non-melanoma skin cancer prevalent in
immune-suppressed transplant recipients and older individuals with a history of chronic sun …
immune-suppressed transplant recipients and older individuals with a history of chronic sun …
Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapy
JC and MY designed experiments, analyzed data, and wrote the manuscript. SMT performed
experiments, analyzed data, and wrote the manuscript. PK contributed to ELISpot assays …
experiments, analyzed data, and wrote the manuscript. PK contributed to ELISpot assays …