Integrative and conjugative elements (ICEs) are a diverse group of mobile genetic elements
found in both Gram-positive and Gram-negative bacteria. These elements primarily reside in …

Horizontal genomics is a new field in prokaryotic biology that is focused on the analysis of
DNA sequences in prokaryotic chromosomes that seem to have originated from other …

Actinobacteria constitute one of the largest phyla among Bacteria and represent gram-
positive bacteria with a high G+ C content in their DNA. This bacterial group includes …

Horizontal transfer of genomic islands (GEIs), that is, chromosomal regions encoding
functions that can be advantageous for the host, plays a key role in bacterial evolution, but …

Conjugative transfer of bacterial plasmids is the most efficient way of horizontal gene
spread, and it is therefore considered one of the major reasons for the increase in the …

Elements that excise and integrate, such as prophages, and transfer by conjugation, such as
plasmids, have been found in various bacteria. These elements appear to have a diversified …

Genetic exchange by conjugation is responsible for the spread of resistance, virulence, and
social traits among prokaryotes. Recent works unraveled the functioning of the underlying …

Abstract The 8–9-Mb Streptomyces chromosome is linear, with a “core” containing essential
genes and “arms” carrying conditionally adaptive genes that can sustain large deletions in …

Entry exclusion is a property of plasmids by which the cells that contain them become bad
recipients in additional conjugation rounds. This work reviews entry exclusion essential …

Small molecules produced by Actinobacteria have played a prominent role in both drug
discovery and organic chemistry. As part of a larger study of the actinobacterial symbionts of …