The outer most layer of the skin, the stratum corneum, consists of corneocytes which are
coated by a cornified envelope and embedded in a lipid matrix of ordered lamellar structure …

This review is the second part of a series which presents the state of the art in stratum
corneum (SC) lipid matrix (LM) research in depth. In this part, the various hypothetical …

Stratum Corneum (SC), the outermost layer of skin, is mainly responsible for skin's barrier
function. The complex lipid matrix of SC determines these barrier properties. In this study …

Omega-O-acyl ceramides such as 32-linoleoyloxydotriacontanoyl sphingosine (Cer [EOS])
are essential components of the lipid skin barrier, which protects our body from excessive …

This review is summarizing an important part of the state of the art in stratum corneum
research. A complete overview on discoveries about the general biophysical and …

Ceramides are known to be a key component of the stratum corneum, the outermost
protective layer of the skin that controls barrier function. In this work, molecular dynamics …

The stratum corneum (SC) provides the main barrier properties in native skin. The barrier
function is attributed to the intercellular lipids, forming continuous multilamellar membranes …

To optimize transdermal application of drugs, the barrier function of the skin, especially the
stratum corneum (SC), needs to be reduced reversibly. For this purpose, penetration …

Ceramides are indispensable constituents of the stratum corneum (SC), the uppermost
impermeable layer of human skin. Ceramides with shorter (four-to eight-carbon acyl chains) …

Ceramides (Cers) with α-hydroxylated acyl chains comprise about a third of all extractable
skin Cers and are required for permeability barrier homeostasis. We have probed here the …