Cancer immunotherapy offers substantive benefit to patients with various tumour types, in
some cases leading to complete tumour clearance. However, many patients do not respond …

Simple Summary Natural killer T (NKT) cells are a subset of lipid-reactive T cells that
enhance anti-tumor immunity. While preclinical studies have shown NKT cell …

During metastasis, cancer cells invade, intravasate, enter the circulation, extravasate, and
colonize target organs. Here, we examined the role of interleukin (IL)-22 in metastasis …

The CCR7 chemokine axis is comprised of chemokine ligand 21 (CCL21) and chemokine
ligand 19 (CCL19) acting on chemokine receptor 7 (CCR7). This axis plays two important …

Today, cancer treatment is one of the fundamental problems facing clinicians and
researchers worldwide. Efforts to find an excellent way to treat this illness continue, and new …

Vaccines are powerful tools that can activate the immune system for protection against
various diseases. As carbohydrates can play important roles in immune recognition, they …

Oligosaccharides are the ubiquitous molecules of life. In order to translate human
bioglycosylation into clinical applications, homogeneous samples of oligosaccharides and …

Lipids, which along with carbohydrates and proteins are among the most important nutrients
for the living organism, have a variety of biological functions that can be applied widely in …

GM3, a typical tumor-associated carbohydrate antigen, is considered as an important target
for cancer vaccine development, but its low immunogenicity limits its application. αGalCer …

Glycosphingolipids (GSLs) are major amphiphilic glycolipids present on the surface of living
cell membranes. They have important biological functions, including maintaining plasma …