The continuing story of T‐cell independent antibodies

D Allman, JR Wilmore, BT Gaudette - Immunological reviews, 2019 - Wiley Online Library
The purpose of this article is to review the role of extrafollicular and T‐cell independent
antibody responses in humoral immunity. We consider two interrelated questions:(a) do T …

Host and parasite responses in human diffuse cutaneous leishmaniasis caused by L. amazonensis

SM Christensen, AT Belew, NM El-Sayed… - PLoS neglected …, 2019 - journals.plos.org
Diffuse cutaneous leishmaniasis (DCL) is a rare form of leishmaniasis where parasites grow
uncontrolled in diffuse lesions across the skin. Meta-transcriptomic analysis of biopsies from …

Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes …

MM El Sayed, H Takata, T Shimizu… - Journal of Controlled …, 2020 - Elsevier
The accelerated blood clearance (ABC) phenomenon, caused in large degree via in vivo
anti-PEG IgM production, is one of obstacles for development of PEGylated liposome and …

Prenatal development and function of human mononuclear phagocytes

M Miah, I Goh, M Haniffa - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
The human mononuclear phagocyte (MP) system, which includes dendritic cells, monocytes,
and macrophages, is a critical regulator of innate and adaptive immune responses. During …

Development of novel S PC-3 gefitinib lipid nanoparticles for effective drug delivery in breast cancer. Tissue distribution studies and cell cytotoxicity analysis

S Nayek, NM Raghavendra, BS Kumar - Journal of drug delivery science …, 2021 - Elsevier
Objective The present work was aimed to develop gefitinib solid lipid nanoparticles (GFT-
SLN) using novel lipids (Lipoid S PC-3) and to analyse its cell cytotoxicity and tissue …

[PDF][PDF] Antibody Synthesis in Vitro

P Martínez, A Iborra - e LS, 2001 - researchgate.net
Several strategies are used to provide immortalized monoclonal antibody-secreting B cells,
and antibodies by recombinant deoxyribonucleic acid (DNA) technology. Monoclonal …

The interactions of invasive bacteria with tissue-resident macrophages

RG Hames - 2023 - figshare.le.ac.uk
Invasive bacteria are likely to encounter macrophages during their course of pathogenesis,
especially if infection progresses to disease. The study of these interactions is crucial for our …

[PDF][PDF] Az egér perifériás nyirokszövetek vaszkuláris-stromális elemeinek differenciálódása és szerepe a limfoid sejtek homeosztázisában

P Balogh - 2020 - real-d.mtak.hu
1. A szokatlan tömörség miatt azonban például nem áll rendelkezésünkre információ arról,
hogy a nagyszámú alkalmazott transzgenikus egértörzs honnan származott, mint ahogyan …

Unaltered intravenous prion disease pathogenesis in the temporary absence of marginal zone B cells

BM Bradford, NA Mabbott - Scientific Reports, 2019 - nature.com
Prion diseases are a unique, infectious, neurodegenerative disorders that can affect animals
and humans. Data from mouse transmissions show that efficient infection of the host after …

[PDF][PDF] On Developing Effective Nanoparticle-Based Vaccines Against Malaria

LM POWLES - scholar.archive.org
Complex diseases (such as malaria) exhibit high degrees of antigenic polymorphism and
complex life cycles. These have hindered the development of vaccine formulations capable …