Homocysteine–from disease biomarker to disease prevention

AD Smith, H Refsum - Journal of internal medicine, 2021 - Wiley Online Library
We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …

Red cell distribution width, anemia, and brain volumetric outcomes among middle-aged adults

MA Beydoun, S Hossain, PH MacIver… - Journal of …, 2021 - content.iospress.com
Background: Anemia and red cell distribution width (RDW) have been linked to poor
cognitive performance, pending studies of underlying mechanisms. Objective: We examined …

Plasma homocysteine and longitudinal change in cognitive function among urban adults

MA Beydoun, HA Beydoun, MF Georgescu… - Journal of Affective …, 2024 - Elsevier
Background Cross-sectional and longitudinal studies have inconsistently linked cognitive
performance and change over time to an elevated level of homocysteine (Hcy), with few …

Vitamin D status and its longitudinal association with changes in patterns of sleep among middle-aged urban adults

MA Beydoun, AE Ng, MT Fanelli-Kuczmarski… - Journal of affective …, 2021 - Elsevier
Objective. We examined relationships of vitamin D status with over time changes in patterns
of sleep in a longitudinal study of Whites and African-American urban middle-aged adults …

Inexpensive, accurate, and stable method to quantitate blood alanine aminotransferase (ALT) levels

P Hartmann, B Schnabl - Methods and Protocols, 2022 - mdpi.com
Alanine aminotransferase (ALT) levels are frequently determined in serum and plasma
samples and are a primary measure to quantitate hepatocellular injury in rodents, humans …

Anthropometric, biochemical, and haematological indicators associated with hyperhomocysteinemia and their relation to global DNA methylation in a young adult …

F Hernandez-Landero, E Sanchez-Garcia… - Epigenetics, 2022 - Taylor & Francis
Increased homocysteine (Hcy) levels have been associated with a higher risk of
cardiovascular and neurodegenerative diseases. Passive DNA demethylation has been …

An efficient LC–MS/MS method for simultaneous determination of four substances in the Hcy metabolism pathway

H Zou, M Liu, Y Li, F Zhao, G Ren - Bioanalysis, 2023 - Taylor & Francis
Aim: This study aimed to develop and validate an efficient LC–MS/MS method for the
simultaneous determination of Hcy, Cys, Met and 5-methyltetrahydrofolate in human serum …

Protective Effects of Fagonia Tenuifolia Methanolic Extracts against Hyperhomocysteinemia Produced by Methionine, by Repeal of Oxidative Stress Markers in Mice

M Hemal, S Zerizer… - Journal of …, 2024 - corescholar.libraries.wright.edu
Natural products were extracted from many Fagonia species, belongs to the Zygophyllaceae
family. They are used currently as drugs, these elements act as free radical scavengers …

Plasma cotinine is positively associated with homocysteine in smokers but not in users of smokeless tobacco

E Söderström, TK Nilsson, J Schneede… - International journal of …, 2021 - mdpi.com
Plasma total homocysteine (tHcy) is a risk marker, and smoking is an established risk factor
for cardiovascular disease. It is unclear if the effect of smoked tobacco on homocysteine is …

Serum folate and homocysteine levels are associated with cardiometabolic risk factors in patients with type 2 diabetes

X Men, J Yang, Y Yan, P Yue, M Zhang, L Gong, S Liu - 2022 - researchsquare.com
Background Previous studies indicate that serum folate is inversely associated with
metabolic syndrome (MetS). This study aims to investigate the association between serum …