Since the definition of the “12 Principles of Green Chemistry” more than 20 years ago,
chemists have become increasingly mindful of the need to conserve natural resources and …

We are entering an era that emphasizes greenness and sustainability. Based on such a
philosophy, it is critical to uncover novel and original sustainable reaction modes for future …

Transition-metal-catalyzed C–H bond functionalizations have had an enormous influence on
organic synthesis in recent times. However, the use of low-abundance 4d and 5d metals is …

In 2007 the members of the ACS Green Chemistry Institute® Pharmaceutical Roundtable
assembled a list of key green chemistry research areas to both identify transformations that …

Conspectus Aromatic structures are widespread motifs throughout organic chemistry, and C–
H activation has been recognized as a major tool for enabling their sustainable and efficient …

Transition metal-catalysed functionalizations of inert C–H bonds to construct C–C bonds
represent an ideal route in the synthesis of valuable organic molecules. Fine tuning of …

Electrooxidation has emerged as an increasingly viable platform in molecular syntheses that
can avoid stoichiometric chemical redox agents. Despite major progress in electrochemical …

Transition metal-catalyzed direct functionalization of C–H bonds is one of the key emerging
strategies that is currently attracting tremendous attention with the aim to provide alternative …

Palladium-catalyzed aerobic oxidation reactions have been the focus of industrial
application and extensive research efforts for nearly 60 years. A significant transition …

Achieving selective C− H activation at a single and strategic site in the presence of multiple
C− H bonds can provide a powerful and generally useful retrosynthetic disconnection. In this …