Background: T and B cell-mediated immunity can be assessed using T cell receptor excision
circle (TREC) and Kappa-deleting recombination excision circle (KREC) analysis …

Newborn bloodspot screening (NBS) began in the early 1960s based on the work of Dr.
Robert “Bob” Guthrie in Buffalo, NY, USA. His development of a screening test for …

Exposure to stress triggers biological changes throughout the body. Accumulating evidence
indicates that alterations in immune system function are associated with the development of …

T cell receptor excision circles (TRECs) are small circularized DNA elements produced
during rearrangement of T cell receptor (TCR) genes. Because TRECs are fairly stable, do …

Background Zellweger syndrome (ZS) is a congenital autosomal recessive disease within
the spectrum of peroxisome biogenesis disorders, characterized by the impairment of …

Thymus depletion is a usual finding in human-immunodeficiency virus (HIV) infected
patients, but a refurbishment of the thymus function in children has been proposed in some …

Omenn 综合征(OS) 是一种罕见的常染色体隐性遗传的免疫缺陷病, 是重症联合免疫缺陷的一种.
其临床表现主要以红皮病, 肝脾和淋巴结肿大, 反复感染为特征, 并可伴有自身免疫表现 …

Актуальность исследования. При существующем уровне рождаемости в Свердловской
области ежегодно появляется около 300 детей с аномалиями развития системы …

Severe combined immunodeficiency (SCID) is the most severe heterogeneous group of
inherited disorders characterized by profound abnormalities such as humoral and cell …

Высокие показатели перинатальной заболеваемости и смертности при осложненном
течении многоплодной беременности обусловливают важность дальнейшего поиска …