The phenomenon of a gene expression burst has been attributed to random transitions
between the active and inactive states of a gene. However, the mechanisms underlying …

Gene transcription is a stochastic process manifested by the mRNA distribution data at the
single-cell level, which can be fitted using the mass function P m that quantifies the …

Gene transcription is a stochastic process manifested by fluctuations in mRNA copy
numbers in individual isogenic cells. Together with mathematical models of stochastic …

Gene transcription is a stochastic process, manifested by heterogeneous distribution of
Messenger RNA (mRNA) copy numbers in a population of isogenic cells. The most …

The stochasticity of transcription can be quantified by mRNA distribution $ P_m (t) $, the
probability that there are $ m $ mRNA molecules for the gene at time $ t $ in one cell …

Gene transcription is a random process in single cells manifested by the observed
distribution of mRNA copy numbers in homogeneous cell populations. A central question is …

Gene transcription is a noisy process, and cell division cycle is an important source of gene
transcription noise. In this work, we develop a mathematical approach by coupling …

Gene transcription is a complex multistep biochemical process, which can create memory
between individual reaction events. On the other hand, many inducible genes, when …

Genetically identical cell populations growing in the same environment show a large degree
of heterogeneity in gene expression profiles, resulting in significant phenotypic …

Randomness in gene transcription can result in fluctuations (noise) of messenger RNA
(mRNA) levels, leading to phenotypic plasticity in the isogenic populations of cells. Recent …