The impact of estrogens and their receptors on immunity and inflammation during infection

AT Harding, NS Heaton - Cancers, 2022 - mdpi.com
Simple Summary Human health is significantly affected by microbial infections. One of the
largest determinants of the outcomes of such infections is the host immune response. Too …

The microbiota-gut-bone axis and bone health

Y Tu, R Yang, X Xu, X Zhou - Journal of leukocyte biology, 2021 - academic.oup.com
The gastrointestinal tract is colonized by trillions of microorganisms, consisting of bacteria,
fungi, and viruses, known as the “second gene pool” of the human body. In recent years, the …

Lactobacillus rhamnosus GG ameliorates osteoporosis in ovariectomized rats by regulating the Th17/Treg balance and gut microbiota structure

M Guo, H Liu, Y Yu, X Zhu, H Xie, C Wei, C Mei… - Gut …, 2023 - Taylor & Francis
Background With increasing knowledge about the gut–bone axis, more studies for
treatments based on the regulation of postmenopausal osteoporosis by gut microbes are …

Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells

M Yu, S Pal, CW Paterson, JY Li… - The Journal of …, 2021 - Am Soc Clin Investig
Estrogen deficiency causes a gut microbiome–dependent expansion of BM Th17 cells and
TNF-α–producing T cells. The resulting increased BM levels of IL-17a (IL-17) and TNF …

The gut microbiome and female health

R Siddiqui, Z Makhlouf, AM Alharbi, H Alfahemi… - Biology, 2022 - mdpi.com
Simple Summary A plethora of studies have highlighted the profound role of the gut
microbiome in human health. However, there is a lack of studies on female health. Given …

Spotlight on the gut microbiome in menopause: current insights

BA Peters, N Santoro, RC Kaplan… - International Journal of …, 2022 - Taylor & Francis
The gut microbiome is an important contributor to human health, shaped by many
endogenous and exogenous factors. The gut microbiome displays sexual dimorphism …

The effects of hormone replacement therapy on the microbiomes of postmenopausal women

MI Dothard, SM Allard, JA Gilbert - Climacteric, 2023 - Taylor & Francis
The sex steroid hormone estrogen plays a number of regulatory roles in female
development. During menopause, estrogen synthesis in the ovaries decreases, which …

Inflammation and gut dysbiosis as drivers of CKD–MBD

P Evenepoel, P Stenvinkel, C Shanahan… - Nature Reviews …, 2023 - nature.com
Abstract Two decades ago, Kidney Disease: Improving Global Outcomes coined the term
chronic kidney disease–mineral and bone disorder (CKD–MBD) to describe the syndrome of …

[HTML][HTML] The role of prunes in modulating inflammatory pathways to improve bone health in postmenopausal women

JJ Damani, MJ De Souza, HL VanEvery, NCA Strock… - Advances in …, 2022 - Elsevier
The prevalence of osteoporosis among women aged 50 y and older is expected to reach
13.6 million by 2030. Alternative nonpharmaceutical agents for osteoporosis, including …

Gut permeability and its clinical relevance in schizophrenia

I Ishida, J Ogura, E Aizawa, M Ota… - …, 2022 - Wiley Online Library
Aim We aimed to examine the gut permeability in patients with schizophrenia and its
relevance to schizophrenia symptoms, medication, cognitive functions, and blood immune …