Cryo-electron microscopy (CryoEM) has become a vital technique in structural biology. It is
an interdisciplinary field that takes advantage of advances in biochemistry, physics, and …

Cryo-EM maps are valuable sources of information for protein structure modeling. However,
due to the loss of contrast at high frequencies, they generally need to be post-processed to …

We review the growing use of machine learning in electron microscopy (EM) driven in part
by the availability of fast detectors operating at kiloHertz frame rates leading to large data …

Cryo-electron microscopy (cryo-EM) has become a powerful tool to resolve high-resolution
structures of biomacromolecules in solution. However, air-water interface induced preferred …

Abstract Videos captured using Transmission Electron Microscopy (TEM) can encode details
regarding the morphological and temporal evolution of a material by taking snapshots of the …

Cryo-electron microscopy (cryo-EM) has become an unrivaled tool for determining the
structure of macromolecular complexes. The biological function of macromolecular …

Cryo-electron tomography is the only technique that can provide sub-nanometer resolved
images of cell regions or even whole cells, without the need of labeling or staining methods …

Highlights•Single particle cryo-EM structure validation is an area of much-needed
development, and has seen significant recent advances.•The reported resolution of a single …

Human cytomegalovirus (HCMV) encodes G protein–coupled receptors (GPCRs) US28 and
US27, which facilitate viral pathogenesis through engagement of host G proteins. Here we …

The power of computer simulations, including machine‐learning, has become an
inseparable part of scientific analysis of biological data. This has significantly impacted the …